首页|Estimation of Body Composition in Dialysis Patients using Segmental Bioimpedance

Estimation of Body Composition in Dialysis Patients using Segmental Bioimpedance

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Accurate estimation of body muscle, fat and fluid volumes in dialysis patients is an important factor to predict outcomes of the disease。Bioimpedance spectroscopy (BIS) has been used to measure extracellular (Re) and intracellular resistance (Ri) with whole body (wBIS) and segmental (sBIS) measurement。40 stable HD patients (22m/18f, age 54。7±11 yrs, height (H) 1。67±0。94 m, weight (Wt) 77。7±17 kg) were studied with wBIS and sBIS compared to the gold standard measurements by MRI and tracer dilution assays (D2O and NaBr) pre dialysis。Multiple linear regression models were constructed with body compartment estimates from the gold standard methods as the dependent variables and bioimpedancederived resistances, Wt, H, and age as independent variables。The results of estimation for fat (r2=0。96 and r2=0。91), for muscle (r2=0。9 and r2=0。88) and for ECV (r2=0。73 and r2=0。59) were from sBIS and wBIS model respectively。In conclusion, the sBIS model is useful to assess body composition in dialysis patients。

componentbody compositionwhole body and segmental bioimpedancedialysisMRI

Fansan Zhu、Mary Carter、Stephan Thijssen、Peter Kotanko、Nathan W Levin

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The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议)论文集

Beijing(CN)

Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009

1-4

2009