CRISPR-Cas12a-Based Detection of SARS-CoV-2 Harboring the E484K Mutation

扫码查看

原文链接

NETL

外文摘要：SARS-CoV-2 is constantly and rapidly evolving→increasing its transmission and disease1。Some mutations like the E484K create a canonical PAM for Cas12a which can be exploited to obtain a differential readout。We report the exploitation of CRISPR-Cas12 to analyse a series of fecal samples from real patients，finding one infection carrying the E484K mutation。

作者：

Roser Montagud-Martínez、Rosa Márquez-Costa、María-Carmen Marqués、Raúl Ruiz、Sandra Albert、Pilar Domingo-Calap、Guillermo Rodrigo

展开 >

作者单位：

I2SysBio,CSIC-Universitat Valencia,46980 Paterna,Spain

会议名称：

International BioDesign Research Conference;Stanford University;Nanjing Agricultural University;University of Warwick

会议母体文献：

The 2nd International BioDesign Research Conference

页码：

1-1

出版时间：

2021