查看更多>>摘要：The authors regret that there are some errors in the description of the "2.10 Positron emission tomography with 2-deoxy-2-[fluorine-18]flu-oro-D-glucose (~18F-FDG PET)" section. The results and analysis of the our data remain correct and unchanged. The correct description of the 2.10 section is detailed as follow: "To evaluate BAT activity, ~18F-FDG PET images were acquired at 14 weeks of age using a small-animal PET Scanner (Triumph? - Gamma Medica-Ideas, Northridge, CA, U.S.A). Briefly, animals were housed 24 h before PET scans at the facility of Nuclear Medicine Laboratory (LIM-43), University of Sao Paulo, Sao Paulo, Brazil. The bolus of 37-55 MBq of ~18F-FDG was administered in the penile vein under adrenergic stimulation or basal conditions. Under stimulated conditions, an intravenous injection of CL316,243 (1 mg/kg) was given 30 min before ~18F-FDG administration. In the basal state, animals received an intravenous saline injection. Images were acquired 45 min after ~18F-FDG injection, with the animal under isoflurane inhalation anesthesia (1.5-3%).
Diptimayee DasAntara BanerjeeAtala Bihari JenaAsim K. Duttaroy...
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查看更多>>摘要：Thyroid dysfunction is the most prevalent endocrine disorder worldwide having an epidemiology of 11% in Indians, 4.6% in the United Kingdom, and 2% in the United States of America among the overall population. The common thyroid disorders include hypothyroidism, hyperthyroidism, Hashimoto's thyroiditis, and thyroid cancer. This review briefly elaborates the molecular regulation and mechanism of thyroid hormone, and its associated thyroid disorders. The thyroid hormones regulate critical biochemical functions in brain development and function. Hypothyroidism is mainly associated with dysregulation of cytokines, increased ROS production, and altered signal transduction in major regions of the brain. In addition, it is associated with reduced antiox-idant capacity and increased oxidative stress in humans. Though 70% of thyroid disorders are caused by heredity, environmental factors have a significant influence in developing autoimmune thyroid disorders in people who are predisposed to them. This drives us to understand the relationship between environmental factors and thyroid dysregulated disorders. The treatment option for the thyroid disorder includes antithyroid medications, receiving radioactive iodine therapy, or surgery at a critical stage. However, antithyroid drugs are not typically used long-term in thyroid disease due to the high recurrence rate. Adjuvant treatment of antioxidants can produce better outcomes with anti-thyroid drug treatment. Thus, Adjuvant therapy has been proven as an effective strategy for managing thyroid dysfunction, herbal remedies can be used to treat thyroid dysfunction in the future, which in turn can reduce the prevalence of thyroid disorders.
查看更多>>摘要：This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies /article-withdrawal). This article has been retracted at the request of the Editor-in-Chief as panels within Figs. 2D and 5D appear similar to each other. Given the comments of Dr Elisabeth Bik regarding this article "This paper belongs to a set of over 400 papers (as per February 2020) that share very similar Western blots with tadpole-like shaped bands, the same background pattern, and striking similarities in title structures, paper layout, bar graph design, and - in a subset - flow cytometry panels", the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request.
查看更多>>摘要：This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies /article-withdrawal). This article has been retracted at the request of the Editor-in-Chief.Panels from Figs. 1B and 3C appear similar to panels from Figure 7E of the article previously published by Yantao Han, Xiuwei Yang, Ning Zhao, Jianjun Peng, Hui Gao and Xia Qiu in the American Journal of Cancer Research 6(12) (2016) 2755-2771 https://www.ncbi.nlm.nih. gov/pmc/articles/PMC5199752/, Fig. 1C of the article published by C.-L. Xue, H.-G. Liu, B.-Y. Li, S.-H. He and Q.-F. Yue in the European Review for Medical and Pharmacological Sciences 23 (2019) 5101-5112 https://www.europeanreview.org/wp/wp-content/uploads/5101-511 2.pdf and Fig. 1C of the article published by Zhao Ma, Xuebin Bao and JunbaoGu in Life Sciences 218 (2019) 47-57 https://doi.org/10.1016/j. lfs.2018.12.027. Also, panels from Fig. 5B appear similar to panels from Fig. 8C of the article published by Kaili Liu, Hui Gao, Qiaoyun Wang, Longyuan Wang, Bin Zhang Zhiwu Han, Xuehong Chen, Mei Han and Mingquan Gao in Cancer Science 109 (2018) 1369-1381 https://doi.org/10.1111/ cas.13575 and Fig. 8D of the article published by Xiangyang Dou, Meihua Wang, Tao Zhang and Jiapei Yao in the Anatomical Record 303 (2020) 3117-3128 https://doi.org/10.1002/ar.24324. Although this article was published earlier than most of the other articles, the Editor decided to retract this article given concerns about the reliability of the data. The first author reported to the journal that the article was submitted without the awareness of the last author and by using an illegitimate email address that included the name of the last author.
查看更多>>摘要：This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies /article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Given the comments of Dr Elisabeth Bik regarding this article "... the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy/pasted from other sources, or computer generated", the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article.
查看更多>>摘要：This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies /article-withdrawal). This article has been retracted at the request of the Editor-in-Chief.Given the comments of Dr Elisabeth Bik regarding this article "... the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy/pasted from other sources, or computer generated", the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article.
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