查看更多>>摘要：The study investigated autonomic regulation during feeding in six-month old infants with a history of excessive crying (EC) and social-behavioral development at 12 and 24 months. When contrasted with non-EC infants (NEC), EC infants had atypical autonomic responses observed as dampened reductions in respiratory sinus arrhythmia (RSA) and decreases in heart period (HP) during feeding. EC infants demonstrated atypical autonomic regulation only if they were bottle-fed, while breastfed EC infants had patterns of autonomic regulation similar to NEC infants. Behavioral data suggest that while a history of EC was related to social-emotional behaviors at 12 and 24 months, breastfeeding may buffer the behavioral effects of EC on sociability at 24 months.
查看更多>>摘要：Memory retrieval of consolidated memories has been extensively studied using "old-new tasks", meaning tasks in which participants are instructed to discriminate between stimuli they have experienced before and new ones. Significant differences in the neural processing of old and new elements have been demonstrated using different techniques, such as electroencephalography and pupillometry. In this work, using the data from a previously published study (Campos-Arteaga, Forcato et al. 2020), we investigated whether machine learning methods can classify, based on single trials, the brain activity and pupil responses associated with the processing of old and new information. Specifically, we used the EEG and pupillary information of 39 participants who completed an associative recall old-new task in which they had to discriminate between previously seen or new pictures and, for the old ones, to recall an associated word. Our analyses corroborated the differences in neural processing of old and new items reported in previous studies. Based on these results, we hypothesized that the application of machine learning methods would allow an optimal classification of old and new conditions.Using a Windowed Means approach (WM) and two different machine learning algorithms -Logistic Regression (WM-LR) and Linear Discriminant Analysis (WM-LDA) -mean classification performances of 0.75 and 0.74 (AUC) were achieved when EEG and pupillary signals were combined to train the models, respectively. In both cases, when the EEG and pupillary data were merged, the performance was significantly better than when they were used separately. In addition, our results showed similar classification performances when fused classification models (i.e., models created with the concatenated information of 38 participants) were applied to individuals whose EEG and pupillary information was not considered for the model training. Similar results were found when alternative preprocessing methods were used.Taken together, these findings show that it is possible to classify the neurophysiological activity associated with the processing of experienced and new stimuli using machine learning techniques. Future research is needed to determine how this knowledge might have potential implications for memory research and clinical practice.
查看更多>>摘要：Individuals who are addicted to drugs often face unfavourable social conditions and difficulty with social adaptation. Both may be closely related to impaired social cognitive ability. This study posits that social cognitive impairments likely arise from blunted social reward processing in drug users. This study aimed to explore the electrophysiological mechanism of social reward processing in people who abstain from using heroin (heroin abstainers). Twenty-eight male heroin abstainers and 27 matched controls completed the social incentive delay task. At the same time, their corresponding behaviour and electroencephalography data were recorded. The feedback-related negativity (FRN) elicited by positive outcomes was significantly more positive than that elicited by negative outcomes for the healthy controls. However, no significant difference in FRN was found between negative and positive outcomes among the heroin abstainers. There was no significant difference in P3 (a positive event-related potential component after FRN) elicited by negative and neutral outcomes in the heroin abstainers. Meanwhile, negative outcomes elicited greater P3 than neutral outcomes in the healthy controls. In addition, this study also found that withdrawal time was negatively correlated with the difference wave of FRN for the heroin abstainers. Heroin abstainers may be hyposensitive to the processing of social reward outcomes. In other words, they may have insufficient motivation to acquire social rewards. Abnormal social reward processing found in heroin abstainers can be improved with an increase in abstinence time. These results deepen our understanding of the social reward impairments associated with chronic drug use.
Barry, Robert J.De Blasio, Frances M.Rushby, Jacqueline A.MacDonald, Brett...
15页
查看更多>>摘要：Auditory stimulus intensity of innocuous tones is generally thought to have a direct effect on the amplitude of ERP components, but these effects have rarely been explored across a wide component range, or in multiple paradigms. Here we investigate component sensitivity to stimulus intensity differences in two studies. Study 1 (N = 36) employed a between-participants paradigm in which repeated trains of standard stimuli were presented as 50 or 80 dB SPL 1000 Hz tones. Study 2 (N = 18) used a within-participant presentation of alternating 60 and 80 dB SPL 1000 Hz tones. Electrode caps with 19 channels (referred to linked ears) generated ERPs covering the first 600 ms of each participant's EEG responses; these were submitted to separate temporal PCAs in each study. A similar series of components was obtained in each study: P1, N1a, N1b, N1c, P2, P3a, P3b, nP3, SW1, and SW2; an N2 was found in Study 2 only. Loud tones in Study 1 produced greater amplitudes in all components except SW1. In Study 2, Loud cf. Soft tones produced smaller P1 and nP3, larger N1 components, P2, and P3a, with no effect on N2, P3b, SW1 or SW2. These results indicate similar sequential processes underlying sensory processing in one- and two-stimulus paradigms, with the later stimulus intensity effects varying with paradigm.
Bautista, FavianaMacDonald, Shannon E.Bauer, Elizabeth A.Cheng, Yuhan...
7页
查看更多>>摘要：Cognitive reappraisal is a well-studied emotion regulation technique that involves changing the meaning of stimuli. To be useful in everyday life, reappraisal's effects would ideally generalize from previously reappraised stimuli to novel, but similar stimuli, saving individuals from needing to generate novel interpretations for similar stimuli. Here, 41 participants were asked to use reappraisal to down-regulate their response to negative pictures from one category (e.g., snakes), and to view negative pictures from another category (e.g., guns) as well as neutral pictures (e.g., plants). In a subsequent task, participants passively viewed novel pictures from all three categories (e.g., snakes, guns, and plants). EEG and subjective ratings of valence and arousal were collected in both tasks. In the reappraisal task, we did not find an effect of reappraisal on the LPP or arousal ratings, but reappraisal reduced ratings of picture unpleasantness. In the second task, negative pictures from the previously reappraised category elicited smaller LPPs than negative pictures from the previously viewed category, though there was no evidence that reappraisal generalized to subjective ratings of pictures. Therefore, at the electrocortical level, cognitive reappraisal may generalize to similar but novel stimuli encountered outside of the reappraisal context. Moreover, meaning change might be more effective in modulating electrocortical response following a delay and in the absence of deliberate attempts to down-regulate emotional response. Nonetheless, reappraisal's effects appear to differ across levels of affective response when similar stimuli are encountered in the absence of willful attempts at reappraisal.
NSTL
Elsevier