首页期刊导航|Skin research and technology
期刊信息/Journal information
Skin research and technology
Munksgaard
Skin research and technology

Munksgaard

0909-752X

Skin research and technology/Journal Skin research and technologySCIEIISTP
正式出版
收录年代

    Issue Information

    2页
      原文链接:
    • NSTL

    A three‐dimensional scar assessment tool for keloid scars: Volume, erythema and melanin quantified

    Francesca RucciaGiovanni ZoccaliLilli CooperClaire Rosten...
    10页
    查看更多>>摘要：Abstract Background There is no non‐invasive objective assessment tool to measure keloid scar characteristics over time. This study aimed to ascertain the ability of the Antera 3D? camera to detect differences in keloid features pre‐ and post‐steroid injection. In order to identify whether those variation could be considered as treatment response predicting factors. Methods Enrolled patients received three intra‐lesional steroid injections at four‐weekly intervals. Images were taken with the Antera 3D camera 12 and 24?weeks after treatment. Keloids’ colour, volume, and area as well as haemoglobin and melanin average levels and variation have been analysed pre‐ and post‐steroid injection. t Tests and relative risk have been used to analyse the significance and association strength of our finding. Results Forty patients have been enrolled in the study. Significant changes as been recorded in keloids’ volume and colour after steroid injection (P?<?0.05). 53% have recorded a Hb reduction showing no recurrence of pathology, patient who had increase in Hb showed an early recurrence. Melanin variation was significant after steroid injection (P?<?0.05) but no correlation has been found with treatment response. Conclusions The Antera 3D camera is able to detect differences in the investigated keloid's features helping in two ways: by providing an objective, longitudinal method to monitor and document changes in scar morphology, and through monitoring haemoglobin change, which strongly correlates to both response to treatment and likelihood of recurrence. Allowing clinicians to identify which patients will respond early, in order to change treatment if necessary, limiting morbidity and costs.
      原文链接:
    • NSTL
    • Wiley

    Validation of the elastic angle for quantitative and visible evaluation of skin elasticity in vivo

    Joonoh MyoungEui Taek JeongMina KimJun Man Lim...
    6页
    查看更多>>摘要：Abstract Background Reduction in skin elasticity due to aging causes skin sagging and wrinkles. Although there are various objective and reliable techniques for measuring skin elasticity, it is difficult to obtain a visual representation of skin elasticity with them. Therefore, we developed a novel device, the Swing anglemeter, and analyzed its effectiveness for measuring skin elasticity of the cheek. Materials and Methods Forty‐five healthy Korean women (age, 23‐60?years) participated. The Swing anglemeter works by dropping a rubber ball on a subject's cheek, which draws a curve as it collides with the cheek. After recording the movement of the ball using the slow‐motion function on a mobile phone, we defined the maximum angle at which the ball bounces off the skin as the elastic angle, using frame‐by‐frame video analysis. Changes in the elastic angle were assessed according to age, and correlation with the Ballistometer? results (Dia‐stron Ltd., Andover, UK) was analyzed for validation. Results Elastic angles differed significantly (P?<?.001) according to age. A negative correlation was found between the elastic angle and age (r?=??.799, P?<?.001). Compared with the Ballistometer? measurements, the elastic angle was negatively correlated with alpha (r?=??.570, P?<?.001); it was positively correlated with the mean coefficient of restitution and area (r?=?.602, P?<?.001 and r?=?.535, P?<?.001, respectively). Conclusion The elastic angle is a useful parameter for reflecting skin elasticity, both quantitatively and visually. Our method can help subjects understand their skin elasticity status. Therefore, we expect the device will be utilized in various fields within the cosmetic industry.
      原文链接:
    • NSTL
    • Wiley

    Establishment of visual assessment for the severity of dark circles in Chinese Han women

    Yimei TanYanwen JiangJiaping ChenHua Sun...
    6页
    查看更多>>摘要：Abstract Objective To establish a visual assessment scale for the severity of dark circles' pigmented and vascular type in Chinese women. Materials and method A total of 269 healthy Chinese women from Shanghai with different degrees of dark circles', both pigmented and vascular types, were evaluated by visual assessment. Photographs of their dark circles were analyzed by image analysis. Results The visual assessment evaluation on classification and severity showed a favorable agreement between the successive measured results. Significant differences from very slight to severe dark circles for pigmented type and vascular type were observed. The severity level by visual assessment was significantly positively correlated with ΔE values while negatively correlated with ΔL values (P?<?.01) in both pigmented and vascular types. Besides, Δa values of vascular type were significantly positively correlated with the ΔE values for dark circles' vascular type. Values between ΔE and ΔL also showed a significant negative correlation (P?<?.01). Conclusion The five‐point visual assessment scale for dark circles of vascular and pigmented types was verified and proved to have good repeatability. The image analysis's objective result proved significant and consistent with the visual assessment and color parameters. This scale could be a useful and effective tool in diagnosing dark circles' severity.
      原文链接:
    • NSTL
    • Wiley

    Biophysical and ultrasonographic changes in early patch/plaque stage of mycosis fungoides, compared with uninvolved skin

    Taraneh YazdanparastKamran YazdaniSaman Ahmad NasrollahiLeila Izadi Firouzabadi...
    6页
    查看更多>>摘要：Abstract Background The goal of this study was evaluation of the skin biophysical properties in early patch/plaque stage of mycosis fungoides (MF) and its comparison with uninvolved skin in order to gain a better understanding of the pathogenesis of diseases. Materials and Methods The stratum corneum hydration, transepidermal water loss (TEWL), surface friction, pH, sebum, melanin, erythema, temperature, elasticity parameters (R0, R2, R5), thickness, and echo density of epidermis and dermis were measured on lesions of 21 patients and compared with controls (average measures of uninvolved perilesional and symmetrical skins) by paired sample t test. Results Stratum corneum hydration (P?<?0.001) and echo density of dermis (P?=?0.044) were significantly lower, whereas pH (P‐value?=?0.007), erythema (P?<?0.001), and melanin content (P?=?0.007) were significantly higher in lesions. There was not any significant difference in TEWL, friction index, sebum, temperature, R0, R2, R5, thickness of epidermis and dermis, and echo density of epidermis between lesions and normal skin. Conclusion Parapsoriasis/MF lesions are specified by a set of certain changes in biophysical properties which are mainly correlated with histological changes. These sets of alterations may help in noninvasive, early diagnosis of parapsoriasis/MF.
      原文链接:
    • NSTL
    • Wiley

    Evaluation of nail surface topography using a three‐dimensional in vivo optical skin imaging system

    Sung Eun LeeKwang Ho YooKapsok LiHyeonji Park...
    8页
    查看更多>>摘要：Abstract Background The analysis of nail surface topography is a subject of ever‐increasing interest in dermatology, especially in cosmetic studies. However, there is no accurate and scientifically sound instrumental method that can identify and provide quantitative data on nail surface topography. Materials and Methods The right index fingers of 78 healthy individuals were examined. The severity of nail roughness was rated by two independent dermatologists on a scale of 1 to 3. Using the phaseshift rapid in vivo measurement of the skin (PRIMOS) system, three‐dimensional microtopography was performed, and the roughness parameter values were calculated and evaluated. The relationship between clinical nail roughness grade and nail roughness parameter values obtained utilizing PRIMOS was evaluated. Results A moderate correlation was found between the roughness parameter values and the clinical roughness grade. Our study showed that an overall relationship exists between the nail roughness parameter values obtained using PRIMOS and clinically observed nail surface changes. Conclusion With further studies, PRIMOS could be a valuable tool for clinicians and researchers for conducting an accurate and objective patient assessment in daily practice and demonstrating effectiveness of different therapies for nail dystrophy or evaluating cosmetic effects of various topical treatments in future clinical trials.
      原文链接:
    • NSTL
    • Wiley

    Technique for analyzing the transfer of colored cosmetics onto face masks

    Juseon LeeMinhye ParkHongbi KimSungeun Kim...
    6页
    查看更多>>摘要：Abstract Background With the rapid spread of COVID‐19, the makeup trend in the cosmetics market is changing as mask‐wearing has become a common practice. This study was conducted to establish an objective and reliable method for analyzing the transfer of colored cosmetics onto face masks. Methods A total of 24 women participated in this test. The participants were requested to wear Korean Filter 94 masks after having applied colored cosmetics on their faces and lips. VISIA‐CR was used to photograph the face, and a camera was used to photograph the mask, which had smeared the cosmetics. Each image was analyzed using the Image‐pro? 10 image analysis software. Results Immediately after applying the cosmetics, the intensity of the face decreased and the redness of the lips increased when compared with the results 30?minutes after washing the face. After wearing a mask, the intensity increased and the redness decreased when compared with immediately after applying the cosmetics. The area before and after the colored cosmetics smeared onto the mask was increased. Conclusion It is expected that this study could be used as a reference for further experiments on analysis of methods for preventing mask stains.
      原文链接:
    • NSTL
    • Wiley

    Effect of scratching and friction on human skin in vivo

    Chengwen FeiYafei XuTing CaoWencai Jiang...
    8页
    查看更多>>摘要：Abstract Objective To investigate effect of scratching and friction on human skin function and functional differences between scratching and friction. Method Forty healthy volunteers were enrolled. Scratching and friction behavior was modeled by scalpel and sandpaper simulation to forearm for 80 times, respectively. Noninvasive bioengineering devices were used to measure basic skin physiological parameters and exfoliated stratum corneum collected and protein quantified. Parameters were recorded at baseline (BL) and after every 20 times interventions (20, 40, 60, and 80 times). Results Compared to BL, transepidermal water loss (TEWL) value increased significantly at both scratched and friction sites (P?<?.001) with a significant higher value for friction (P?<?.001). There was no significant difference in stratum corneum hydration (SCH) value postscratching (P?>?.05), while it decreased first and then increased significantly at friction site (P?<?.001). Roughness values (contract (CONT), variety (VAR), and scaliness (SEsc)) were raised significantly at both sites (P?<?.001). Net change in CONT and SEsc values of friction was higher than scratched sites (P?>?.05). There was no significant difference in blood flow after both scratching and friction (P?>?.05). Quantity of keratinocyte protein from friction sites was statistically higher than scratching after 80 times interventions (P?<?.05). Conclusion Both noninvasive detections and protein quantification indicated more damage from friction, which may have significance for behavior guidance of patients with pruritus and implication for further investigation.
      原文链接:
    • NSTL
    • Wiley

    Anatomic and diagnostic considerations of facial mobility for understanding the effectiveness of facial massage: A pilot study

    Minoru YamadaYoshitake YamadaYoichi YokoyamaItsuko Okuda...
    7页
    查看更多>>摘要：Abstract Background The effectiveness of facial massage is often explained by the resulting increases in the blood and lymphatic flow. However, it is difficult to explain the lifting effect on the cheeks. The aim of this study was to analyze facial mobility to further current understanding of the effectiveness of facial massage. Materials and Methods Two kinds of analytical methods were designed using a cadaveric head as well as advanced computed tomography (CT). The cadaveric face was divided into three sections, and three different colors of ink were injected into each section. It was kept in a supine position for 24?hours, and the ink distribution was observed. Upright and supine CT examinations were performed on six healthy adult volunteers. The images of both were superimposed by a three‐dimensional image analysis system, and changes in facial contours were analyzed. Results The three colors of ink spread craniocaudally and were distributed differently from the gravitational vector. When both CT images were superimposed, two distinct lines were formed, which represented overlapping of the facial contours due to the two different CT images. These lines were found to correspond to the border of each color of the ink. Conclusion Focusing on the mobility of the face, the soft tissue of the face had vertical mobility, and it was speculated that this mobility is involved in the effectiveness of facial massage. Our results could provide useful information for cosmetic treatment and contribute to the collection of scientific knowledge for anti‐aging medicine.
      原文链接:
    • NSTL
    • Wiley

    Evaluation of subclinical chronic sun damage in the skin via the detection of long‐lasting ultraweak photon emission

    Yu GabeKatsuya TakedaMegumi TobiishiSho Kikuchi...
    8页
    查看更多>>摘要：Abstract Background It is well known that solar radiation accelerates skin photoaging. To evaluate subclinical photodamage in the skin especially from the early phase of ultraviolet (UV)‐induced damage, we have focused on ultraweak photon emission (UPE), also called biophotons. Our previous study reported that the amount of long‐lasting UPE induced by UV, predominantly from lipid peroxidation, is a valuable indicator to assess cutaneous photodamage even at a suberythemal dose, although it was only applied to evaluate acute UV damage. The aim of this study was to further investigate whether long‐lasting UPE could also be a useful marker to assess subclinical chronic sun damage in the course of skin photoaging. Materials and Methods Forty‐three Japanese females in their 20s were recruited and were divided into two groups according to their history of sun exposure based on a questionnaire (high‐ and low‐sun‐exposure groups). Several skin properties on the cheek and outer forearm were measured in addition to UV‐induced UPE. Results Among the skin properties measured, water content, average skin roughness, and the lateral packing of lipids in the stratum corneum were significantly deteriorated in the high‐sun‐exposure group as were changes in some skin photoaging scores such as pigmented spots and wrinkles. In addition, those skin properties were correlated with the UPE signals, suggesting the possible impact of oxidative stress on chronic skin damage. Conclusion Subtle oxidative stress detected by long‐lasting UPE may contribute to subclinical cutaneous damage at the beginning phase of chronic sun exposure, which potentially enhances skin photoaging over a lifetime.
      原文链接:
    • NSTL
    • Wiley