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Elsevier

0165-9936

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    Advances in 3D printed sensors for food analysis

    Santos, Danilo M. dosCardoso, Rafael M.Migliorini, Fernanda L.Facure, Murilo H. M....
    20页
    查看更多>>摘要:Food quality control is of utmost importance for human safety and health, requiring efficient and reliable analytical methods for food analysis. The advantageous features such as versatility, simplicity, repro-ducibility, accuracy, and relatively low cost have enabled 3D printing techniques to be employed in the design of portable sensors for the detection of varied food contaminants. This review aims at discussing recent advances in the use of 3D printing technologies for the design of sensing platforms and providing comprehensive insights into the application of such platforms for the detection of food contaminants such as heavy metals, pesticides, pathogens, mycotoxins, spoilage, allergens and adulterations on food as well as for the food flavor analysis. We focus on two points: 1) an overview of the most explored 3D printing technologies and transduction sensing mechanisms, and 2) the current state-of-the-art 3D printing for the preparation of sensors for monitoring food safety and quality. Emphasis is also placed on the development of hand-held and consumer-friendly 3D printed sensors, while challenges and obstacles that must be overcome to enable their practical application in food safety control along the food supply chain are also summarized. (c) 2022 Elsevier B.V. All rights reserved.

    Recent advances in sampling and sample preparation for effect- directed environmental analysis

    Huang, ShuyaoFan, MenggeWawryk, NicholasQiu, Junlang...
    13页
    查看更多>>摘要:Complex chemicals have been imposing adverse effects on the environment and organisms. Conventional chemical-based quantitative analysis may not comprehensively reveal the major contributors responsible for the adverse effects, such as nonregulated analysis of unknown chemicals. Effect-directed analysis (EDA) is a powerful approach to identify the contributors. Recent advancement in integration of various sampling and sample preparation strategies with EDA has improved identification of causative components in a sample. Various workflows of sampling, enrichment and fractionation in an integrated format or sequential and parallel steps are developed to shorten analysis time and increase resolution, sensitivity, throughput and coverage of analytes. Herein, we review recent advances in combination of sampling and sample preparation techniques with EDA to study toxic chemicals in sediment, water, biota, and other environmental compartments. The current status and experience lead to discussion on the existing challenges, perspectives for future research development and applications in this field.(c) 2022 Elsevier B.V. All rights reserved.

    Portable instruments for on-site analysis of environmental samples

    Duan, ChunfengLi, JiaminZhang, YuanhaoDing, Kun...
    21页
    查看更多>>摘要:On-site analysis can provide qualitative or/and quantitative information of samples at the sample location. Up to date, a variety of portable instruments have been available for on-site analysis, some of which have even been commercialized. For an on-site analysis, all the steps including sampling, sample preparation, separation/non-separation, detection and data processing must be carried out on-site. Portable GC and GC-MS have been widely used in on-site environmental sample analysis. Moreover, there are many types of optical instruments based on absorption, emission or scattering have also been used for field analysis, each with its own advantages and application capabilities. Due to the limits of detection and selectivity of instruments being used, sample preparation is used in most applications. This review summarizes the current advances of on-site sample preparation devices, on-site GC/GC-MS, and on-site optical instruments in detail. Finally, the future development direction of these field instruments is also discussed. (c) 2022 Elsevier B.V. All rights reserved.

    Metal organic framework based sensors for the detection of food contaminants

    Marimuthu, MurugaveluArumugam, Selva SharmaJiao, TianhuiSabarinathan, Devaraj...
    25页
    查看更多>>摘要:Food contamination is a global concern. Therefore, it is necessary to identify, remove, and control persistent hazards and harmful constituents from products. Metal organic frameworks (MOF) are a class of compounds with unique chemical and physical properties offered in food safety standards. MOF-based sensors have emerged as promising complementary and alternative analysis methods to conventional detection methods, owing to their high absorbency, strong luminous features, and cost-effectiveness. In this review, we summarize various MOF-based sensors, describe their principles, and explore their applications in detecting pesticides, antibiotics, pathogens, and mycotoxins in terms of their sensitivity and multiplexing capability. The limitations and challenges of using MOF-based sensors for efficient and precise evaluation of food are also discussed. Finally, we discuss the purpose of developing and improving MOF material sensors, in the context of food security.(c) 2022 Elsevier B.V. All rights reserved.

    Nano-labeled materials as detection tags for signal amplification in immunochromatographic assay

    Su, ZixianDou, WenchaoLiu, XiangjiangPing, Jianfeng...
    18页
    查看更多>>摘要:The immunochromatographic assay (ICA) was widely used in rapid detection in many fields due to its advantages such as economy, simplicity, sensitivity, and specificity all the time. Like fluorescence, colored, magnetic nanoparticles (NPs) have become the most commonly used signal tags in ICA. As an ancient detection technology, improving the analytical sensitivity of ICA has always been a hot topic for scholars. However, its superiority in many booming rapid testing methods has become relatively weaker. But, after the outbreak of the epidemic in 2020, many researchers successively reported on the immu-nological assay of the epidemic, and the nucleic acid testing and vaccination are also being carried out across the country to ensure personal safety, which made this ancient test method favoured by experts and scholars again. This means that the ICA is still one of the most rapid and economical detection methods when faced with sudden virus disasters.With the increasing demand for rapid detection, improving the sensitivity or shortening the detection times of ICA based on NPs/nanomaterials has become the focus of the study. Now, it is urgently needed to research convenient, economical, and sensitive novel immunosensors to cope with unknown viruses and others based on the advantages of the ICA that immediate and rapid on-site detection. Therefore, this article briefly reviews the emerging nano-labeled particles used to improve the sensitivity of ICA in rapid detection, introduces the development of ICA in real-time detection, and summarizes the current status of their applications in immunoassay of viruses, proteins, molds, agricultural, and veterinary drugs, toxins, metabolites et al. based on three basic NPs with the excellent properties such as luminescent NPs, magnetic NPs, and colored NPs. To improve the sensitivity of ICA, we also introduce the detection limit of several types of new NPs with higher optical properties in immunoassay, the three new methods of amplifying the signal of immunoprobe, and the application of optical composite nanomaterials in ICA in recent years, hope to provide a reference for the development of new nano-labeled materials and new immunodetection methods to improve the sensitivity of immunoassay so that it can meet the increasing needs of rapid detection.(c) 2022 Elsevier B.V. All rights reserved.

    Unconventional and user-friendly sampling techniques of semi-volatile organic compounds present in an indoor environment: An approach to human exposure assessment

    Marc, MariuszZabiegala, Bozena
    13页
    查看更多>>摘要:The commonly applied solutions used to assess the potential risk of human exposure to semi-volatile organic compounds (SVOCs) are based on the investigation of biological samples collected in an invasive or non-invasive manner. For SVOCs, which are typically introduced to humans through the respiratory system, dermal adsorption, or digestive system, sampling solutions generally used in the indoor environments are classified as active and passive. From the user's perspective, the most convenient method to assess the potential risk is the use of an analytical tool that combines the benefits of passive and non-invasive sampling techniquesduse of an unconventional personal sampler such as a silicone wristband, brooch, dog tag, cotton gauze, or viscose wiper. Despite the advantages of this method, the aforementioned techniques require further analytical research owing to the differences in the results of human exposure assessment owing to the lack of standards and unified sampling protocols. (c) 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

    Design strategies, current applications and future perspective of aptasensors for neurological disease biomarkers

    Marrazza, GiovannaUslu, BengiErkmen, CemTig, Gozde Aydogdu...
    18页
    查看更多>>摘要:The increasing trend in the incidence of neurological disease (NDs) cases is a major challenge for societies. The aggregation of misfolding some proteins can cause neurological disorders in the brain. Early detection of the NDs plays a critical, because prolongs in the diagnostic process will lead to delayed initiation of treatment procedures, other diseases affecting the central nervous system will reduce the effectiveness of the treatment. Early detection of the NDs can be achieved by aptasensors that are used aptamers as biorecognition elements due to their unique selective, sensitive, and cost-effective properties. In this review, the recent progress on aptasensors for NDs biomarkers was provided in terms of the aptamers, construction principles of aptasensors, signal transduction methods, performance properties, applications, and advantages/limitations. In addition, appropriate aptamer selection methods and characterization steps are described. Moreover, future aspects are discussed for further research for developing novel aptamers and aptasensors in clinical diagnostics. (C) 2022 Elsevier B.V. All rights reserved.

    Application of deep eutectic solvents in bioanalysis

    Andruch, VasilVarfalvyov, AlicaHalko, RadoslavJatkowska, Natalia...
    19页
    查看更多>>摘要:The application of deep eutectic solvents (DESs) is sharply surging as a green alternative to conventional solvents due to their unique properties in terms of simplicity of preparation, designability and low cost. A great deal of attention has been paid to the application of these green solvents in analytical chemistry in recent years, and a lot of interesting work has been reported. This review summarizes the most relevant applications of DESs in bioanalysis related to both sample preparation and analyte quantification. Special attention is devoted to the discussion of practical applications for various types of biological samples (blood, plasma, serum, urine, saliva, hair, tear, sweat), with a focus on the advantages of DES-based methods over traditional ones. We cover the articles that were available online up to the end of January 2022. The applications of the reported techniques are summarized in tables. (c) 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

    Recent advances in carbon nanotube-based biosensors for biomolecular detection

    Dai, BenhuiZhou, RuiyunPing, JianfengYing, Yibin...
    15页
    查看更多>>摘要:Earlier studies have found a relationship between biomolecules in living organisms and diseases. The monitoring of abnormal physical conditions and the timely detection of diseases can reduce the mortality rate and ensure the physical health of organisms. Traditional laboratory methods for analyzing pathogenic factors usually require long time, high cost, and complex process. Biosensors can provide timely and accurate analysis of metabolites in the body to provide support for modern treatment. The unique physico-chemical and photoelectric properties of carbon nanotubes (CNTs) can improve the performance of biosensors, such as the larger surface area for better catalyst fixation and the CNTmodified electrodes for faster electron transfer which provide more sensitive detection of biosensors. Typical applications of CNT-based sensors are described in detail in this article, including detections of glucose detection, DNA, protein, amino acids, and neurotransmitter. The detection performance of sensors can be improved through the continuous improvement of materials and structures. Finally, a summary and future outlook for CNT-based biosensors are provided. (c) 2022 Published by Elsevier B.V.

    Application of omics approaches for assessing microplastic and nanoplastic toxicity in fish and seafood species

    Bhagat, JackyZang, LiqingNishimura, NorihiroShimada, Yasuhito...
    8页
    查看更多>>摘要:Numerous reports on the occurrence of microplastics/nanoplastics (MP/NP) in aquatic environments have triggered severe concerns about the adverse impact of these particles on aquatic organisms and their transfer through food webs. The past few years have seen an emerging interest among toxicologists in the use of omics technologies to elucidate the response of fish and other aquatic organisms to environmental contaminants. Omics approaches, such as transcriptomics, proteomics, microbiomics, and metabolomics, have advanced our knowledge of MP/NP-related toxicity. The integration of multi-omics provides a deeper understanding of the toxicity mechanisms and pathways involved. This review provides comprehensive updates and status on applying omics technologies to study the MP/NP-related toxicity in fish and seafood species. Compared with other toxicants, the signature profile or finger-print of MP/NP still requires further development. Further, a robust regulatory oversight is required to monitor and minimise MP/NP contamination in commercially-important aquatic species. (c) 2022 Elsevier B.V. All rights reserved.