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World neurosurgery
Elsevier
World neurosurgery

Elsevier

1878-8750

World neurosurgery/Journal World neurosurgeryAHCISCIISTP
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    Contralateral Supracerebellar-Transtentorial Approach for Posterior Mediobasal Temporal Cavernous Malformation Resection

    Frisoli, Fabio A.Baranoski, Jacob F.Catapano, Joshua S.Lang, Michael J....
    1页

    Indocyanine Green-Assisted Endoscopic Transorbital Excision of Lateral Orbital Apex Cavernous Hemangioma

    Ng, Ben Chat FongMak, Calvin Hoi KwanChan, Nok LunLam, Chun Wah...
    1页

    Paleopathology of Endocranial Lesions: A Possible Case of a Middle Meningeal Artery Aneurysm in an Etruscan Child from Pontecagnano (Southern Italy)

    Riccomi, GiuliaBareggi, AlessiaMinozzi, SimonaAringhieri, Giacomo...
    6页

    Introducing the Posterior Condylar Emissary Vein as an Effective Surgical Landmark for Optimizing the Standard Retrosigmoid Approach: An Anatomo-Imaging Study

    Koutsarnakis, ChristosDrosos, EvangelosKomaitis, SpyridonMazarakis, Nektarios...
    6页
    查看更多>>摘要:OBJECTIVE: There is a lack of definite anatomical landmarks for the inferior extension of the standard retro-sigmoid approach. In this study, we evaluated whether the posterior condylar emissary vein (PCEV) can be used as an intraoperative landmark for optimizing the surgical corridor. x25a0; METHODS: We performed the standard retrosigmoid approach on 5 formalin-fixed and latex-injected cadaveric specimens and measured the distance between the PCEV near its bony canal and the vertebral artery (VA). In addi-tion, vascular reconstructions of thin-sliced preoperative computed tomography (CT) scans were studied in 40 pa-tients and the relationship between these 2 vessels was evaluated. An illustrative case is also included. x25a0; RESULTS: The PCEV was consistently identified on both sides of cadaveric specimens and in 87.5% and 82.5% of the left and right sides of the included CT scans, respectively. The average distance between the part of the PCEV near its osseous canal and the VA was measured to be between 8.4 mm and 8.6 mm in the specimens and between 9.2 mm and 9.3 mm in the CT scans. This distance offers a safe and effective plane of dissection during the standard retro-sigmoid approach and allows easy access to the foramen magnum. x25a0; CONCLUSIONS: The PCEV near its bony canal proved to be an easy, straightforward, safe, and effective operative landmark with which the surgeon can extend the soft tis-sue dissection and bony exposure towards the foramen magnum. This maneuver provides ample access to the cisterna magna for cerebrospinal fluid drainage and in-creases visibility and surgical maneuverability to the entire cerebellopontine angle.

    Microsurgical Treatment for a Ruptured Posterior Inferior Cerebellar Artery Aneurysm: A 3-Dimensional Surgical Video and Anatomic Landmarks Review

    Mulato, Jose Ernesto ChangRiechelmann, Guilherme SalemiAlejandro, Sebastian AnibalPaganelli, Samantha Lorena...
    1页

    Microsurgical Excision of Ruptured Lenticulostriate Artery Aneurysm

    Fredrickson, Vance L.Makarenko, SergeHollon, Todd C.Rennert, Robert C....
    1页

    Bone Graft Options in Spinal Fusion: A Review of Current Options and the Use of Mesenchymal Cellular Bone Matrices

    Viola, Anthony, IIIAppiah, JudeDonnally, Chester J., IIIKim, Yong H....
    7页
    查看更多>>摘要:BACKGROUND: Spinal fusion is the mainstay treatment for various spinal conditions ranging from lumbar and cervical stenosis to degenerative spondylolisthesis as well as extensive deformity corrections. A new emerging category of allograft is cellular bone matrices (CBMs), which take allogeneic mesenchymal stem cells and incorporate them into an osteoconductive and osteoinductive matrix. This study reviewed the current spinal fusion options and new emerging treatment options. METHODS: Articles were searched using PubMed. The search included English publications since January 1, 2014, using the search terms "cellular bone matrix," "mesenchymal stem cells spinal fusion," "spinal arthrodesis AND mesenchymal stem cells," and "spine fusion AND cellular bone matrix." RESULTS: Spinal fusion is accomplished through the use of allografts, auto grafts, and bone graft substitutes in combination or alone. An emerging category of allograft is CBMs, in which an osteoconductive and osteoinductive matrix is filled with mesenchymal stem cells. Studies demonstrate that CBMs have achieved equivalent or better fusion rates compared with traditional options for anterior cervical discectomy and fusions and posterolateral lumbar fusions; however, the studies have been retrospective and lacking control groups and therefore not ideal. CONCLUSIONS: Many treatment options have been successfully used in spinal fusion. Newer allografts such as CBMs have shown promising results in both animal and clinical studies. Further research is needed to determine the therapeutic dose of mesenchymal stem cells delivered within CBMs.

    Intraoperative Continuous Neuromonitoring for Vestibular Schwannoma Surgery: Real-Time, Quantitative, and Functional Evaluation

    Matsushima, KenKohno, MichihiroSakamoto, HirokiIchimasu, Norio...
    1页

    Metastatic Lesions of the Clivus: A Systematic Review

    Jozsa, FelixDas, Joe M.
    15页
    查看更多>>摘要:BACKGROUND: Metastatic lesions of the clivus are extremely rare, having previously been estimated as representing 0.02% of all intracranial tumors. Owing to its close intracranial relationship with the clivus before entering the cavernous sinus, clinical palsies of the sixth cranial nerve have been classically associated with destructive lesions of this structure. METHODS: A comprehensive search of PubMed was conducted for studies of patients with metastasis to the clivus from primary cancer at any site. Studies reported in English in the past 20 years from our last search on April 12, 2021 were included. The data collected included patient age, sex, symptoms at presentation, histopathology and treatment timeline of the primary tumor, treatment, follow-up, and mortality. RESULTS: After the literature review, 46 studies reporting on 58 patients with clivus metastasis were included in the final analysis. The mean age of the patients was 57.5 years, and 39 were male (67.2%). The most common sites of the primary tumor were the prostate (22%), gastrointestinal tract (15%), lung (13%), and kidney (11%). In 43% of patients, symptoms of clivus metastasis had pre-sented before the diagnosis of primary cancer was known, and 71% of the pa-tients had presented with sixth nerve palsy. Of the 58 patients, 53% had -ndergone surgery, and 37% had received adjuvant radiotherapy. Of the 58 pa-tients, 25% had received radiotherapy alone. The endoscopic transsphenoidal approach to the clivus was almost uniquely used for surgical management. Survival data were available for 31 patients. Death had occurred at a mean of 9.4 months after the presentation of clivus metastasis. A strong correlation was found between the interval from primary cancer to the presentation of clivus metastasis and mortality. CONCLUSIONS: Although an extremely rare occurrence, clivus metastasis should be considered in patients with a history of malignancy, in particular, prostate malignancy, presenting with new-onset isolated sixth nerve palsy.

    Adult Posterior Fossa Anaplastic Ependymoma, Case Series and Literature Review

    Hsu, Huang-, IHsu, Shu-ShongChung, Wen-YuhYip, Chi-Man...
    5页
    查看更多>>摘要:OBJECTIVE: Ependymomas are rare central nervous system tumors. The current treatment strategy is gross total tumor removal. Whether adjuvant therapy will be beneficial is controversial. We retrospectively analyzed 3 cases of World Health Organization (WHO) grade III posterior fossa anaplastic ependymomas treated with different treatment modalities. We aimed to identify possible treatment options for infratentorial WHO grade III anaplastic ependymoma in adults. METHODS: We performed a retrospective analysis of 3 patients diagnosed with infratentorial anaplastic ependymomas in our institution from 2016 to 2020. The demographic data were documented. This case series of 3 patients does not meet the Department of Health and Human Services definition of research and does not need Institutional Review Board approval. All patients' informed consents have been obtained. RESULTS: One patient underwent subtotal tumor resection combined with adjuvant radiotherapy and Gamma Knife radiosurgery while the other 2 patients -nderwent gross total tumor removal combined with Gamma Knife radiosurgery or adjuvant radiotherapy. Tumors recurred in the first patient 20 months later, while the other 2 patents did not develop recurrence. The modified Rankin scale scores of these patients were 1, 0, and 0. All patients are followed up with regular magnetic resonance imaging at our facility. CONCLUSIONS: The strategy for treating WHO grade III anaplastic ependymomas is controversial, but gross total tumor resection remains the key element. Adjuvant stereotactic radiosurgery after tumor removal might be considered if radiotherapy is not an option. The role of chemotherapy is unclear, and the use of chemotherapy should be tailored to individual patients.