查看更多>>摘要：? 2022Epidermoid tumors are slow-growing, benign, congenital lesions.1 They commonly arise in the cerebellopontine angle, fourth ventricle, suprasellar region, or spinal cord.2 Symptoms may include hearing loss, facial pain, and headaches. The management options include observation or surgical resection. If the patient has symptoms, surgical resection is the treatment option of choice with the goal of gross total resection. In Video 1, we discuss the microsurgical technique for the resection of a right cerebellopontine angle epidermoid tumor. A 22-year-old male patient presented with chronic headache, decreased right-sided hearing, right facial pain, and right facial twitching. Magnetic resonance imaging revealed the characteristic finding of an epidermoid tumor, which appeared as isointense on T1 and hyperintense on T2 with diffusion-weighted imaging. The patient was taken to the operating room, and a retrosigmoid craniotomy was performed on the basis of the transverse and sigmoid sinuses. The tumor capsule was opened, and the tumor was decompressed by removing the internal components consisting of epithelial keratin and cholesterol crystals, allowing for a gross total resection to be achieved. The patient's postoperative computed tomography scan showed no residual tumor, and the patient was discharged on postoperative day 1 in stable condition.
查看更多>>摘要：? 2022 Elsevier Inc.Intramedullary spinal cord metastases (ISCMs) are rare, representing 8.5% of central nervous system metastases and 5% of intramedullary lesions.1 With the advent of immunotherapy leading to longer-term survival for cancer patients, intramedullary metastases are on the rise.2 A 43-year-old female presented with acute right leg weakness and sensory loss (Video 1). Magnetic resonance imaging revealed an avidly enhancing mass in the spinal cord at T6 with associated edema. Surgical resection was performed for tumor debulking to stabilize and ideally improve neurologic function, as well as for tissue acquisition for molecular profiling and targeted therapy. ISCMs are typically entered via midline myelotomy after a standard posterior exposure.3 However, on dural opening and visualization of the spinal cord, it was apparent that the tumor involved the right T6 nerve root. The decision was then made to enter the lesion via the T6 dorsal root entry zone (DREZ).4 Microsurgical resection of the tumor was performed with the aid of ultrasound and D-wave motor monitoring. Postoperative magnetic resonance imaging showed gross total resection and the patient was discharged to acute rehabilitation with increased right leg weakness and stable sensation. We demonstrate that for ISCM involving the exiting nerve root, DREZ myelotomy is a viable alternative to midline myelotomy. We strongly recommend use of D-wave monitoring in such cases as it clearly impacted our ability to maximize the resection. This is the first video where the DREZ approach is emphasized along with utilization of D-wave monitoring. The patient consented to the surgical procedure and the use of intraoperative video for education purposes.
查看更多>>摘要：? 2022 Elsevier Inc.Extracranial artery dissections (EADs) represent leading causes of stroke in young patients, but are uncommon in the general population, thus making it challenging to conduct clinical trials and large observational studies. In this technical video, we present 2 adult patients with cervical internal carotid artery (ICA) dissection treated with flow diverters (Video 1). The first patient come to our attention without symptoms. He had a history of acute ischemic stroke owing to dissection of the right cervical ICA in 2013. He was on double antiplatelet therapy, and he had recurrent colorectal bleeding. Magnetic resonance imaging confirmed right frontal gliosis and occlusion of the right ICA with collaterals from the external carotid artery and showed a double lumen dissection of the left cervical ICA. The second patient was admitted to our emergency department with right tongue and vocal cord palsy. Computed tomography documented 2 carotid pseudoaneurysms, the bigger one on the right side. Flow diversion was successful in both patients. In 15%–20% of patients with EAD, multiple cervical arteries are affected. In EAD, stenosis resolution or recanalization occurs in 33%–90% of patients within 6 months. Dissecting aneurysms are reported to resolve or decrease in size in 40%–50% of patients, but can also increase in size. There are currently no controlled clinical trials comparing endovascular therapy and antithrombotic treatment with antithrombotic therapy alone in patients with carotid EAD, and only some reports have demonstrated the efficacy of angioplasty and stenting. However, we recommend some further reading on this topic.1-5
查看更多>>摘要：? 2022 Elsevier Inc.Decompressive craniectomy has been adopted as a possible therapeutic option for extreme cases of traumatic brain injury and malignant ischemic stroke. The history of decompressive craniectomy, though, involves civilian and military discoveries that have been progressively confused and even forgotten. The syndrome of the trephined was introduced in 1939 as a feeling of tenderness, discomfort, and insecurity located at the site of craniectomy. Forty years later, in 1977, the sinking skin flap syndrome was defined as new-onset neurologic deficits or even coma associated with marked skin depression at the site of craniectomy, indicating urgent need for cranioplasty. These 2 syndromes illustrate the paradigm shift of the indications for cranioplasty, which have evolved from cosmetic reasons in the 1940s to cerebral metabolism improvement in the early 21st century.
查看更多>>摘要：? 2022 Elsevier Inc.An otherwise healthy 57-year-old man presented with intermittent low back pain and was incidentally found to have a left-sided paraspinal mass invading the spinal canal and causing spinal cord compression. He underwent a T11-12 hemilaminectomy, facetectomy, and instrumented fusion for a gross total resection with a good clinical outcome. Pathology revealed the lesion to be a ganglioneuroma. Ganglioneuroma is a rare and interesting pathology. These tumors are benign peripheral neuroblastic tumors derived from the neural crest and found along the entire neuroaxis. Tumors come to clinical attention if they cause symptomatic compression of neural structures or are found incidentally on imaging. Additionally, as these tumors share a common lineage with pheochromocytomas, systemic symptoms can be observed resulting from secretion of vasoactive peptides. The pathologic diagnosis of ganglioneuroma is predominantly based on morphology.
查看更多>>摘要：? 2021Arteriovenous malformations (AVMs) are a highly complex array of abnormal arteries and veins that directly fistulize without intervening capillary beds.1 As AVMs can differ in size, location, and morphology, specific clinical management is determined for each individual patient, in conjunction with their specific goals and needs.2 This Video demonstrates the resection of an AVM located in the language area of eloquent cortex of a 38-year-old opera singer. The patient presented to the emergency department with a new-onset seizure. Magnetic resonance imaging including task-based functional imaging demonstrated a left post temporal AVM with associated hemosiderin-stained white matter and language activation just posterior to the lesion. Awake microsurgical resection was recommended given her career as an opera singer and the high-risk location of the AVM in proximity to eloquent language cortex, with additional goals of preventing further risk of hemorrhage and reduction in the risk of epilepsy. The patient underwent a left temporoparietal craniotomy with direct electrical stimulation-based language mapping and monitoring along with microsurgical resection of the AVM with image guidance, confirmed with intraoperative indocyanine green angiography. Postoperative angiography demonstrated no residual AVM with preservation of normal arterial and venous anatomy. At follow-up, the patient was clinically intact, seizure free, and off all antiepileptic medications. At 3 months, she resumed her career as an opera singer. Awake resection with intraoperative functional mapping can be used for select small AVMs to avoid injury to functional tissue and allow more aggressive resection of potentially epileptogenic tissue.
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