查看更多>>摘要:New research on Digestive System Disea ses and Conditions-Pancreatitis is the subject of a report. According to news reporting from Gansu, People's Republic of China, by NewsRx journalists, researc h stated, "The purpose of the research is to design an algorithm to predict the occurrence of acute respiratory failure (ARF) in patients with acute pancreatiti s (AP). We collected data on patients with AP in the Medical Information Mart fo r Intensive Care IV database." The news correspondents obtained a quote from the research from the Department o f General Surgery, "The enrolled observations were randomly divided into a 70 % training cohort and a 30 % validation cohort, and the observations in the training cohort were divided into ARF and non-ARF groups. Feature engine ering was conducted using random forest (RF) and least absolute shrinkage and se lection operator (LASSO) methods in the training cohort. The model building incl uded logistic regression (LR), decision tree (DT), k-nearest neighbours (KNN), n aive bayes (NB) and extreme gradient boosting (XGBoost). Parameters for model ev aluation include receiver operating characteristic (ROC) curve, precision-recall curve (PRC), calibration curves, positive predictive value (PPV), negative pred ictive value (NPV), true positive rate (TPR), true negative rate (TNR), accuracy (ACC) and F1 score. Among 4527 patients, 445 patients (9.8 %) expe rienced ARF. Ca, ALB, GLR, WBC, AG and BUN have been included in the prediction model as features for predicting ARF. The AUC of XGBoost were 0.86 (95 % CI 0.84-0.88) and 0.87 (95 %CI 0.84-0.90) in the training and valid ation cohorts. In the training cohort, XGBoost demonstrates a true positive rate (TPR) of 0.662, a true negative rate (TNR) of 0.884, a positive predictive valu e (PPV) of 0.380, a negative predictive value (NPV) of 0.960, an accuracy (ACC) of 0.862, and an F1 score of 0.483. In the validation cohort, XGBoost shows a TP R of 0.620, a TNR of 0.895, a PPV of 0.399, an NPV of 0.955, an ACC of 0.867, an d an F1 score of 0.486."