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中国化学快报（英文版）
中国化学快报（英文版）

梁晓天

月刊

1001-8417

cclbj@imm.ac.cn

010-63165638

100050

北京市先农坛街1号

中国化学快报（英文版）/Journal Chinese Chemical LettersCSCDCSTPCD北大核心SCI
查看更多>>本刊是由中国科协主管、中国化学会主办、中国医学科学院药物所承办的学术期刊，是由著名化学家梁晓天院士主编。是中国化学界通向世界的窗口，内容覆盖化学全领域。本刊的办刊宗旨是“新、快、准”，我们将坚持这个宗旨，力求及时反映化学研究中各个相关领域内的最新进展及热点问题，主要读者群是科研人员、研究生、大学教师。现已被国内外多家数据库收录，如SCI　Search、Chemical Abstract、Research Alert、Chemistry Citation Index、《日本科技文献速报》、万方数据数字化期刊群、中国学术期刊过刊全文数据库、中国学术期刊（光盘版）、中国学术期刊文摘、中文期刊全文数据库、俄罗斯Рж期刊源等。
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    Synthesis of amine-pillar[5]arene porous adsorbent for adsorption of CO2 and selectivity over N2 and CH4

    Hui LiYanxing QiJia ChenJuanjuan Wang...
    226-231页
    查看更多>>摘要：A novel amine-modified pillar[5]arene bonded porous silica adsorbent(DETA-P5S)was designed to be applied to dynamic CO2 adsorption and selective separation of CO2 over N2 and CH4 gases mixture.The results demonstrated that reasonable introduction of DETA into the BE-P5 bonded silica support has sig-nificantly increased the adsorption capacity of CO2.The DETA-P5S has the optimal adsorption capacity of 9.1 mmol/g with 5 vol％CO2 at 40 ℃.The main reason of this increased capacity could be attributed to the enhanced CO2 diffusion into porous adsorbent for its better dispersion in the pores of amine-pillar[5]arene cavity and active site of DETA.Furthermore,the dynamic saturation adsorption capacities of DETA-P5S were 7.11(0.37)and 6.18(0.44)mmol/g for CO2/N2 and CO2/CH4,respectively,both the gas mixtures showed high separation selectivity.Simultaneously,the DETA-P5S can maintain outstanding CO2 adsorption capacity after fifteen regeneration cycles.Consequently,the designed DETA-P5S could serve as a promising adsorbent for CO2 capture and storage.
      原文链接:
    • 万方数据

    Rational design of dual sites induced local electron rearrangement for enhanced photocatalytic oxygen activation

    Ruru LiQian LiuHui LiFengbin Sun...
    232-237页
    查看更多>>摘要：Efficient activation of molecular oxygen(O2)is considered a promising technique for the removal of an-tibiotics.However,how to effectively regulate electrons distribution to promote O2 activation remains a challenge at present.In this study,phosphorus and sodium co-doped carbon nitride(PNaCN)were designed to rearrange the electrons distribution to activate O2 for the degradation of tetracycline.The generation of·O2-was innovatively observed via in-situ O2 fitting Fourier transform infrared(FTIR)spec-troscopy,demonstrating the outstanding O2 activation ability of PNa5.Density functional theory(DFT)further confirmed that the rational co-doping led to the rearrangement of local electrons,resulting in electron-rich Na sites and electron-deficient P sites.These sites exhibited greater susceptibility to O2 ad-sorption and charge transfer.Besides,the degradation rate of tetracycline was increased by 2.44 times using co-doped CN.This study provides a new inspiration for enhancing O2 activation by inducing elec-trons rearrangement.
      原文链接:
    • 万方数据
    • 维普

    Composition and size distribution of wintertime inorganic aerosols at ground and alpine regions of northwest China

    Haijiao LiuQiao FengYu HuangFeng Wu...
    238-242页
    查看更多>>摘要：Water-soluble inorganic ions(WSIIs)play a pivotal role in atmospheric chemical reactions,particularly influencing the formation of secondary particulate matter.A comprehensive grasp of the vertical distri-bution of atmospheric pollutants holds immense significance in understanding the diffusion and trans-portation of these pollutants.This study investigates the WSIIs of PM2.5 and size-segregated particles at the top(～2060m a.s.l.)and foot of Mt.Hua during the winter of 2020.All the measured ions present significant higher concentrations(1.9～6.9 times)at the foot than the top.Cl-and K+at the foot are more than 4 times of those at the top,whereas Ca2+and Mg2+are only 1.3-1.9 times higher.The particle size distribution of NO3-,SO42-,K+and Cl-demonstrate a single peak distribution(0.7-1.1μm)at the foot,but with a bimodal distribution(0.7-1.1μm and 4.7-5.8μm)at the top.These differences suggest that the aerosol at the alpine region is mainly transported via long-distance from Northwest/North China,but limited influenced by vertical transport through valley breeze.The changes of concentration and size dis-tribution of WSIIs in dust event and non-dust period indicate that the effects of dust event on aerosols at ground surface were weaker than that of the free troposphere of Guanzhong Plain.Notably,our study underscores the dominant influence of NO3-in shaping the gas-particle distribution of ammonia within the winter free troposphere.Our results highlight the significant role of long-range transport on aerosols in the free troposphere in Guanzhong Plain,Northwest China.
      原文链接:
    • 万方数据
    • 维普

    Nitrogen-rich carbon for catalytic activation of peroxymonosulfate towards green synthesis

    Yu YaoJinqiang ZhangYantao WangKunsheng Hu...
    243-248页
    查看更多>>摘要：Nitrogen-doped carbon(N-C)materials have demonstrated exceptional performances in activating perox-ymonosulfate(PMS)for environmental remediation.However,accommodating higher nitrogen contents remains challenging in N-C due to the thermodynamic instability of C-N skeleton.In this study,we pro-posed an innovative epitaxial growth approach to synthesize two-dimensional N-C nanosheets.Leverag-ing the abundant amino groups supplied by the polymer dots as growing sites,we successfully attained a high nitrogen level and spontaneously introduced abundant structural defects in the carbon framework.The resulting N-C nanosheets exhibited outstanding catalytic activity for the activation of PMS toward selective oxidation of diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1,4-DHP)into diethyl 2,6-dimethylpyridine-3,5-dicarboxylate,which serves as a valuable intermediate in the synthesis of vari-ous pharmaceutical compounds.Comprehensive experimental and characterization investigations verified that the nitrogen sites and defects are the primary active sites for PMS activation and selective oxidation of 1,4-DHP.This work offered an efficient approach for the fabrication of high-nitrogen-loading carbon materials for catalytic oxidation reactions.
      原文链接:
    • 万方数据
    • 维普

    Efficient and selective photocatalytic nitrite reduction to N2 through CO2 anion radical by eco-friendly tartaric acid activation

    Jingtai BiYupeng ChengMengmeng SunXiaofu Guo...
    249-253页
    查看更多>>摘要：In this study,the environmentally friendly precursor,tartaric acid(TA),was employed for the genera-tion of CO2 anion radical(CO2·-)in an advanced UV/TA/Fe3+system to reduce the hazardous NO2--N in wastewater.To optimize this process,various factors,including the dosage of Fe3+,TA,and pH,were sys-tematically investigated for their impact on the reduction process.Under the conditions of 3 mmol/L Fe3+dosage,10 mmol/L TA dosage,and a pH of 2.5,NO2--N was effectively removed from the water within 60 min,selectively transformed into N2,with a remarkable N2 selectivity of 91.2％.In the optimal condi-tions,the NO2-N reduction mechanism in the UV/TA/Fe3+system and the critical role of CO2·-were illus-trated.Finally,this study explored the reduction of real nitrified seawater using the UV/TA/Fe3+system.The results demonstrated that the UV/TA/Fe3+system could completely eliminate NO2--N and achieve a N2 selectivity of up to 90％,with minimal interference from coexisting ions.This work holds promising implications for the environmentally benign treatment of nitrite-polluted wastewater.
      原文链接:
    • 万方数据

    Tuning Stark effect by defect engineering on black titanium dioxide mesoporous spheres for enhanced hydrogen evolution

    Bingke ZhangDongbo WangJiamu CaoWen He...
    254-259页
    查看更多>>摘要：Defects can strongly affect the lattice,strain,and electronic structures of nanomaterials photocatalysts,like a double-edged sword of both positive significance and negative influence on photocatalytic per-formances.To date,most studies into defects only partially elucidated their beneficial or detrimental roles in photocatalysis.However,a quantitative understanding of the photocatalytic performances modu-lated by defect concentration still needs to be discovered.Here,a series of TiO2-X mesoporous spheres(MS)with different oxygen vacancy concentrations for photocatalytic applications were prepared by high-temperature chemical reduction.The link between oxygen vacancy concentration and photocatalytic per-formance was successfully established.The localization of carriers dominated by the Stark effect is first enhanced and then weakened with increasing oxygen vacancy concentration,which is a crucial factor in explaining the double-edged sword role of defect concentration in photocatalysis.As the reduction tem-perature rises to 300 ℃,carrier localization dominated by the quantum-confined Stark effect maximizes the separation ability of photo generated electron hole pairs,thus exhibiting the best catalytic perfor-mance for photocatalytic hydrogen production and the degradation of organic pollutants,as demonstrated by a hydrogen evolution rate of 523.7 μmol g-1 h-1 and a ninefold higher RhB photodegradation rate compared to TiO2 MS.The work offers excellent flexibility for precisely constructing high-performance photocatalysts by understanding vacancy engineering.
      原文链接:
    • 万方数据
    • 维普

    Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics

    Xiaoxiao WangBolun WangFenfen JiJie Yan...
    260-265页
    查看更多>>摘要：Parkinson's disease(PD)is an aging-associated neurodegenerative movement disorder with increasing morbidity and mortality rates.The current gold standard for diagnosing PD is clinical evaluation,which is often challenging and inaccurate.Metabolomics and lipidomics approaches have been extensively ap-plied because of their potential in discovering valuable biomarkers for medical diagnostics.Here,we used comprehensive untargeted metabolomics and lipidomics methodologies based on liquid chromatography-mass spectrometry to evaluate metabolic abnormalities linked with PD.Two well-characterized cohorts of 288 plasma samples(143 PD patients and 145 control subjects in total)were used to examine metabolic alterations and identify diagnostic biomarkers.Unbiased multivariate and univariate studies were com-bined to identify the promising metabolic signatures,based on which the discriminant models for PD were established by integrating multiple machine learning algorithms.A 6-biomarker predictive model was constructed based on the omics profile in the discovery cohort,and the discriminant performance of the biomarker panel was evaluated with an accuracy over 81.6％both in the discovery cohort and val-idation cohort.The results indicated that PC(40:7),eicosatrienoic acid were negatively correlated with severity of PD,and pentalenic acid,PC(40:6p)and aspartic acid were positively correlated with severity of PD.In summary,we developed a multi-metabolite predictive model which can diagnose PD with over 81.6％accuracy based on this unique metabolic signature.Future clinical diagnosis of PD may benefit from the biomarker panel reported in this study.
      原文链接:
    • 万方数据

    Metabolome profiling by widely-targeted metabolomics and biomarker panel selection using machine-learning for patients in different stages of chronic kidney disease

    Yao-Hua GuYu ChenQing LiNeng-Bin Xie...
    266-272页
    查看更多>>摘要：Chronic kidney disease(CKD)is an increasingly prevalent medical condition associated with high mortal-ity and cardiovascular complications.The intricate interplay between kidney dysfunction and subsequent metabolic disturbances may provide insights into the underlying mechanisms driving CKD onset and pro-gression.Herein,we proposed a large-scale plasma metabolite identification and quantification system that combines the strengths of targeted and untargeted metabolomics technologies,i.e.,widely-targeted metabolomics(WT-Met)approach.WT-Met method enables large-scale identification and accurate quan-tification of thousands of metabolites.We collected plasma samples from 21 healthy controls and 62 CKD patients,categorized into different stages(22 in stages 1-3,20 in stage 4,and 20 in stage 5).Us-ing LC-MS-based WT-Met approach,we were able to effectively annotate and quantify a total of 1431 metabolites from the plasma samples.Focusing on the 539 endogenous metabolites,we identified 399 significantly altered metabolites and depicted their changing patterns from healthy controls to end-stage CKD.Furthermore,we employed machine-learning to identify the optimal combination of metabolites for predicting different stages of CKD.We generated a multiclass classifier consisting of 7 metabolites by machine-learning,which exhibited an average AUC of 0.99 for the test set.In general,amino acids,nucleotides,organic acids,and their metabolites emerged as the most significantly altered metabolites.However,their patterns of change varied across different stages of CKD.The 7-metabolite panel demon-strates promising potential as biomarker candidates for CKD.Further exploration of these metabolites can provide valuable insights into their roles in the etiology and progression of CKD.
      原文链接:
    • 万方数据
    • 维普

    4-Aminoazobenzene:A novel negative ion matrix for enhanced MALDI tissue imaging of metabolites

    Ran WuDongxu JiangHao HuChenyu Yang...
    273-277页
    查看更多>>摘要：Endogenous metabolites play key functions in many important physiological and biochemical processes.The comprehensive in situ detection and direct imaging of metabolites in bio-tissues by matrix-assisted laser desorption/ionization mass spectrometry imaging(MALDI-MSI)is very important for understand-ing complex and diverse biological processes and has become an essential aspect of spatial omics.In this work,4-aminoazobenzene(AAB)was successfully screened and optimized as a new negative ion(-)MALDI matrix to enhance the in situ detection and imaging of metabolites in tissues using MALDI-MSI.Obviously,AAB exhibited superior properties in terms of ultraviolet absorption,background ion in-terference,matrix morphology,and metabolite ionization efficiency.AAB was used for in situ detection and imaging of metabolites in rat brain and germinating Chinese yew seed tissue sections,where 264 and 339 metabolite ion signals were successfully detected and imaged using(-)MALDI-MS,respectively.In addition,high-resolution imaging of mouse eyeball section using MALDI-timsTOF MSI with spatial res-olution of up to 10 pm was successfully carried out,showing that AAB is an efficient(-)MALDI matrix for capturing high-resolution images of metabolites in biological tissue sections.
      原文链接:
    • 万方数据
    • 维普

    Dynamic deformylation of 5-formylcytosine and decarboxylation of 5-carboxylcytosine during differentiation of mouse embryonic stem cells into mouse neurons

    Yang FengYang-Qing TianYong-Qiang ZhaoSheng-Jun Chen...
    278-283页
    查看更多>>摘要：Regulation of cell fate requires the establishment and erasure of 5-methylcytosine(5mC)in genomic DNA.The formation of 5mC is achieved by DNA cytosine methyltransferases(DNMTs),whereas the removal of 5mC can be accomplished by various pathways.Aside from ten-eleven translocation(TET)-mediated ox-idation of 5mC followed by thymine DNA glycosylase(TDG)-initiated base excision repair(BER),the di-rect deformylation of 5-formylcytosine(5fC)and decarboxylation of 5-carboxylcytosine(5caC)have also been discovered as the novel DNA demethylation pathways.Although these novel demethylation path-ways have been identified in stem cells and somatic cells,their precise roles in regulating cell fate re-main unclear.Here,we differentiate mouse embryonic stem cells(mESCs)into mouse embryoid bodies(mEBs),followed by further differentiation into mouse neural stem cells(mNSCs)and finally into mouse neurons(mNeurons).During this sequential differentiation process,we employ probe molecules,namely 2'-fluorinated 5-formylcytidine(F-5fC)and 2'-fluorinated 5-carboxyldeoxycytidine(F-5caC),for metabolic labeling.The results of mass spectrometry(MS)analysis demonstrate the deformylation and decarboxy-lation activities are progressively decreased and increased respectively during differentiation process,and this opposite demethylation tendency is not associated with DNMTs and TETs.
      原文链接:
    • 万方数据
    • 维普