查看更多>>摘要：The aim of this study is to fabricate Zr-based bulk metallic glass matrix composites(BMG-MCs)for bio-medical usage and subject them to a comprehensive and far-reaching analysis with respect to their mechanical properties,biocorrosion resistance,biocompatibility,and interactions with biofilms that all may arise from their chemical compo-sitions and unusual disordered internal structure.In this study,we fabricate Zr40Ti15Cu10Ni10Be25,Zr50Ti15Cu10Ni10Be25,and Zr40Ti15Cu10Ni5Si5Be25 alloys and confirm their glassy matrix nature through differential scanning calorimetry(DSC)and scanning electron microscopy(SEM)analyses.The mechanical properties,assessed via nanoindentation,demon-strate the high hardness,strength,and elasticity of the pro-duced materials.Corrosion resistance is investigated in simulated body fluid,with Zr-based BMG-MCs exhibiting superior performance compared to conventional biomedical materials,including 316L stainless steel and Ti6A14V alloy.Biocompatibility is assessed using human fetal osteoblastic cell line hFOB 1.19,revealing low levels of cytotoxicity.The study also examines the potential for biofilm formation,a critical factor in the success of biomedical implantation,where bac-terial infection is a major concern.Our findings suggest,as never reported before,that Zr-based BMG-MCs,with their unique composite glassy structure and excellent physico-chemical properties,are promising candidates for various biomedical applications,potentially offering improved per-formance over traditional metallic biomaterials.
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