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中国神经再生研究(英文版)
中国康复医学会
中国神经再生研究(英文版)

中国康复医学会

旬刊

1673-5374

bwb@nrronline.com

024-23381085

110004

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中国神经再生研究(英文版)/Journal Neural Regeneration ResearchCSCDCSTPCD北大核心SCI
查看更多>>SCI收录杂志!!! 本刊为英文版杂志,以国际通用语言研究最前沿、最热点的神经再生问题。创刊起点高,评估论文研究成果的学术标准高,对论文语言表述水平的要求高。 刊物宗旨: 2006年创刊,面向国际、立足国际,以办好一本国际神经再生学科界专家公认的专业性学术期刊为工作目标,主要发表神经再生领域基础及应用基础研究方面的学术文章。 出版重点: 2009年本刊重点出版对神经损伤修复过程中原位神经干细胞以及移植的神经干细胞作用机制的研究,出版神经组织工程、神经退行性疾病组织形态学变化以及中医药对神经细胞、神经组织再生过程中生理、病理结构变化影响的相关研究文章。面向国际,立足国际,关注全球范围内具有创新性的抑制、促进或影响神经细胞、神经组织再生结构变化相关机制的研究,关注由此而发生的一系列功能变化及其相互关系。 感兴趣神经解剖学、病理学、生理学、生物化学、药理学、免疫学、发育学等来自多学科、多层面的题材,感兴趣发表以基础实验性研究为主的揭示大脑皮质、海马、松果体、神经胶质细胞、脊髓神经元、周围神经元以及运动和感觉神经损伤与再生的研究原著,对有助于认识神经再生正常和异常机制的临床类文章,如罕见病例报告、调查分析等也可纳入范围。 欢迎文章从理论假设、研究方法、模型制备、影像学技术等多个视角描述神经再生的相关特点,为读者提供该领域最有价值的学科进展信息及其最新的理论观点,增强对神经再生复杂机制、学说和病理发生过程的理解。一般文章2000-4000单词。 非常注重出版时效。投稿15~30天编辑部采用随机盲法抽取国际评审专家审稿,符合采用标准的文章进入修稿程序,力求出版周期120~180天,以保证高质量优秀稿件抢先出版。 收录情况: 科学引文索引(SCI) 2006年被SCI引文库收录8篇 2008年1月至2008年7月被SCI收录文章188篇 美国生物学文献数据库(BIOSIS) 美国《化学文摘》(CA) 荷兰《医学文摘库/医学文摘》(EM) 波兰《哥伯尼索引》(IC) 中国英文版科技期刊数据库(统计源期刊) 中国科学引文数据库(核心期刊) 2007年被CA收录247篇,被EM收录173篇
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    Lipid droplets in the nervous system:involvement in cell metabolic homeostasis

    Yuchen ZhangYiqing ChenCheng ZhuangJingxuan Qi...
    740-750页
    查看更多>>摘要:Lipid droplets serve as primary storage organelles for neutral lipids in neurons,glial cells,and other cells in the nervous system.Lipid droplet formation begins with the synthesis of neutral lipids in the endoplasmic reticulum.Previously,lipid droplets were recognized for their role in maintaining lipid metabolism and energy homeostasis;however,recent research has shown that lipid droplets are highly adaptive organelles with diverse functions in the nervous system.In addition to their role in regulating cell metabolism,lipid droplets play a protective role in various cellular stress responses.Furthermore,lipid droplets exhibit specific functions in neurons and glial cells.Dysregulation of lipid droplet formation leads to cellular dysfunction,metabolic abnormalities,and nervous system diseases.This review aims to provide an overview of the role of lipid droplets in the nervous system,covering topics such as biogenesis,cellular specificity,and functions.Additionally,it will explore the association between lipid droplets and neurodegenerative disorders.Understanding the involvement of lipid droplets in cell metabolic homeostasis related to the nervous system is crucial to determine the underlying causes and in exploring potential therapeutic approaches for these diseases.

    Role of copper chelating agents:between old applications and new perspectives in neuroscience

    Rosalba LeuciLeonardo BrunettiVincenzo TufarelliMarco Cerini...
    751-762页
    查看更多>>摘要:The role of copper element has been an increasingly relevant topic in recent years in the fields of human and animal health,for both the study of new drugs and innovative food and feed supplements.This metal plays an important role in the central nervous system,where it is associated with glutamatergic signaling,and it is widely involved in inflammatory processes.Thus,diseases involving copper(Ⅱ)dyshomeostasis often have neurological symptoms,as exemplified by Alzheimer's and other diseases(such as Parkinson's and Wilson's diseases).Moreover,imbalanced copper ion concentrations have also been associated with diabetes and certain types of cancer,including glioma.In this paper,we propose a comprehensive overview of recent results that show the importance of these metal ions in several pathologies,mainly Alzheimer's disease,through the lens of the development and use of copper chelators as research compounds and potential therapeutics if included in multi-target hybrid drugs.Seeing how copper homeostasis is important for the well-being of animals as well as humans,we shortly describe the state of the art regarding the effects of copper and its chelators in agriculture,livestock rearing,and aquaculture,as ingredients for the formulation of feed supplements as well as to prevent the effects of pollution on animal productions.

    Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

    Minghuang GaoXinyue WangShijie SuWeicheng Feng...
    763-778页
    查看更多>>摘要:Meningeal lymphatic vessels form a relationship between the nervous system and periphery,which is relevant in both health and disease.Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to antigen delivery and immune cell activation.The advent of novel genomic technologies has enabled rapid progress in the characterization of myeloid and lymphoid cells and their interactions with meningeal lymphatic vessels within the central nervous system.In this review,we provide an overview of the multifaceted roles of meningeal lymphatic vessels within the context of the central nervous system immune network,highlighting recent discoveries on the immunological niche provided by meningeal lymphatic vessels.Furthermore,we delve into the mechanisms of crosstalk between meningeal lymphatic vessels and immune cells in the central nervous system under both homeostatic conditions and neurodegenerative diseases,discussing how these interactions shape the pathological outcomes.Regulation of meningeal lymphatic vessel function and structure can influence lymphatic drainage,cerebrospinal fluid-borne immune modulators,and immune cell populations in aging and neurodegenerative disorders,thereby playing a key role in shaping meningeal and brain parenchyma immunity.

    Infiltration by monocytes of the central nervous system and its role in multiple sclerosis:reflections on therapeutic strategies

    Guangyong ZhangQing YaoChubing LongPengcheng Yi...
    779-793页
    查看更多>>摘要:Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation.Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process.Monocytes play a significant role in neuroinflammation,and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis,leading to improved patient outcomes.This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention:the activation of bone marrow hematopoiesis,migration of monocytes in the blood,and penetration of the blood-brain barrier by monocytes.Finally,we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences.As activated microglia resemble monocyte-derived macrophages,it is important to accurately identify the role of monocyte-derived macrophages in disease.Depending on the roles played by monocyte-derived macrophages at different stages of the disease,several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis.Here,we discuss possible strategies to target monocytes in neurological diseases,focusing on three key aspects of monocyte infiltration into the central nervous system,to provide new ideas for the treatment of neurodegenerative diseases.

    Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging

    Neville NgMichelle NewberyNicole MilesLezanne Ooi...
    794-796页

    Injury/ischemia-induced stem cells:up-to-date knowledge and future perspectives for neural regeneration

    Takayuki Nakagomi
    797-798页

    Insights from a proteomic atlas of human Alzheimer's disease brain tissue

    Tomas KavanaghEleanor Drummond
    799-800页

    Decoding complexity:the need to enhance precision and streamline spatial understanding in neuroscience

    Sameehan MahajaniArmita SalahiBrenda GonzalezCharlotte Nelson...
    801-802页

    Antisense oligonucleotides provide optimism to the therapeutic landscape for tauopathies

    Glenn A.HarrisLauren R.Hirschfeld
    803-804页

    Mitochondria-cGAS-STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

    José M.Izquierdo
    805-807页