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中华创伤杂志（英文版）
中华创伤杂志（英文版）

王正国

双月刊

1008-1275

cjtrauma@163.com

023-68757483

400042

重庆市渝中区大坪长江支路10号

中华创伤杂志（英文版）/Journal Chinese Journal of TraumatologyCSCDCSTPCD北大核心
查看更多>>中华医学会主办，中华医学会创伤学分会承办。本刊是全英文高级学术刊物，是中华医学会系列杂志之一。主要对外报道我国创伤学及相关学科的成果与进展，全面反映我国创伤医学的成就与水平，促进和指导我国创伤学研究的发展，提高临床救治水平；同时将国外相应领域进展及动态介绍给中国读者。它使中国的创伤医学走向世界，使外国读者了解中国，促使国内外创伤医学的交流与合作。
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    PTSD:Past,present and future implications for China

    Yao-Guang ZhouZhi-Lei ShangFan ZhangLi-Li Wu...
    187-208页
    查看更多>>摘要：There has been a long history since human beings began to realize the existence of post-traumatic symptoms.Posttraumatic stress disorder(PTSD),a diagnostic category adopted in 1980 in the Diag-nostic and Statistical Manual of Mental Disorders-Ⅲ,described typical clusters of psychiatric symptoms occurring after traumatic events.Abundant researches have helped deepen the understanding of PTSD in terms of epidemiological features,biological mechanisms,and treatment options.The prevalence of PTSD in general population ranged from 6.4％to 7.8％and was significantly higher among groups who un-derwent major public traumatic events.There has been a long way in the studies of animal models and genetic characteristics of PTSD.However,the high comorbidity with other stress-related psychiatric disorders and complexity in the pathogenesis of PTSD hindered the effort to find specific biological targets for PTSD.Neuroimage was widely used to elucidate the underlying neurophysiological mecha-nisms of PTSD.Functional MRI studies have showed that PTSD was linked to medial prefrontal cortex,anterior cingulate cortex and sub-cortical structures like amygdala and hippocampus,and to explore the functional connectivity among these brain areas which might reveal the possible neurobiological mechanism related to PTSD symptoms.For now,cognitive behavior therapy-based psychotherapy,including combination with adjunctive medication,showed evident treatment effects on PTSD.The emergence of more effective PTSD pharmacotherapies awaits novel biomarkers from further funda-mental research.Several natural disasters and emergencies have inevitably increased the possibility of suffering from PTSD in the last two decades,making it critical to strengthen PTSD research in China.To boost PTSD study in China,the following suggestions might be helpful:(1)establishing a national psychological trauma recover project,and(2)exploring the mechanisms of PTSD with joint effort and strengthening the indigenized treatment of PTSD.
      原文链接:
    • NETL
    • NSTL
    • 维普
    • 万方数据

    Oxytocin receptor variant rs53576 genotype is associated with dysphoric arousal symptoms of DSM-5 posttraumatic stress disorder in Chinese earthquake survivors

    Cheng-Qi CaoLi WangRuo-Jiao FangGen Li...
    209-213页
    查看更多>>摘要：Purpose:Evidence suggests that the oxytocin receptor(OXTR)gene may be involved in the psychopa-thology of posttraumatic stress disorder(PTSD).This study aimed to investigate the effects of OXTR rs53576 genotype on PTSD symptoms introduced in the Diagnostic and Statistical Manual,Fifth Edition(DSM-5).Methods:This study was a cross-sectional study conducted among 1140 adults who had personally experienced the Wenchuan earthquake.PTSD symptoms were measured with the PTSD checklist for DSM-5.A custom-by-design 2×48-Plex SNPscanTM Kit were used to determine the OXTR rs53576.Multiple regression models were used to analyze the independent and interactive effects of OXTR rs53576 genotype and earthquake exposure on the severity of total PTSD symptoms and different di-mensions of PTSD symptoms.Results:The results revealed that the rs53576 genotype could significantly predict PTSD symptoms(β = 0.055,p = 0.045).Further analysis showed that the rs53576 genotype was only significantly associated with dysphoric arousal symptoms of PTSD(β = 0.080,p = 0.005).The rs53576 genotype x earthquake exposure interaction had no significant effect on different symptom clusters(p＞0.05).Conclusion:This study showed that the rs53576 genotype was only associated with the dysphoric arousal symptoms but not with other symptom clusters of PTSD.These findings support the role of the OXTR on the psychopathology of PTSD and help us to understand the genetic basis of PTSD.
      原文链接:
    • NETL
    • NSTL
    • 维普
    • 万方数据

    Trajectories of mental health symptoms predict long-term quality of life among Wenchuan adolescent survivors:A 10-year follow-up study

    Zi-Juan MaXiao-Yan ChenTong WangShu-Ling Xu...
    214-220页
    查看更多>>摘要：Purpose:Previous studies usually examine the associations between psychological distresses and quality of life(QOL)with a variable-centred approach,while little is known about the effect of the individual variance in time-varying changes of psychological distresses on QOL Therefore,this study aimed to examine whether individual variance in psychological distresses during the early phases post-earthquake would develop different QOL's levels among adolescent survivors 10-year after the Wen-chuan earthquake.Methods:Data were extracted from the Wenchuan Earthquake Adolescent Health Cohort Study.The current study included 744 adolescent survivors who effectively completed surveys at 6 months,24 months,and 10 years after the earthquake.Self-report questionnaires were administered to collect in-formation on socio-demographic characteristics,earthquake exposure,life events,anxiety symptoms,depressive symptoms,posttraumatic stress symptoms(PTSS),and QOL.Data were analysed using hier-archical multiple regression.Results:Trajectories of psychological distresses were classified as follow:resistance(anxiety 40.73％;depression 54.70％;PTSS 74.46％),recovery(anxiety 17.20％;depression 9.27％;PTSS 10.35％),delayed dysfunction(anxiety 10.35％;depression 18.15％;PTSS 6.18％),and chronicity(anxiety 31.72％;depression 17.88％;PTSS 9.01％).After controlling covariates,hierarchical multiple regression only revealed that the anxiety trajectory with delayed dysfunction remained significantly predictive for four domains of QOL(physical health,psychological health,social relationships,and environment).Conclusion:The current study highlights the importance of focusing on the variations in trajectories of anxiety symptoms among disaster survivors and providing individualized mental health services to improve survivors'QOL.
      原文链接:
    • NETL
    • NSTL
    • 维普
    • 万方数据

    Military-related posttraumatic stress disorder and mindfulness meditation:A systematic review and meta-analysis

    Lu-Na SunJing-Wen GuLi-Jun HuangZhi-Lei Shang...
    221-230页
    查看更多>>摘要：Purpose:Posttraumatic stress disorder(PTSD)is a significant global mental health concern,especially in the military.This study aims to estimate the efficacy of mindfulness meditation in the treatment of military-related PTSD,by synthesizing evidences from randomized controlled trials.Methods:Five electronic databases(Pubmed,EBSCO Medline,Embase,PsychINFO and Cochrane Library)were searched for randomized controlled trials focusing on the treatment effect of mindfulness medi-tation on military-related PTSD.The selection of eligible studies was based on identical inclusion and exclusion criteria.Information about study characteristics,participant characteristics,intervention de-tails,PTSD outcomes,as well as potential adverse effects was extracted from the included studies.Risk of bias of all the included studies was critically assessed using the Cochrane Collaboration's tool.R Statis-tical software was performed for data analysis.Results:A total of 1902 records were initially identified and screened.After duplicates removal and title&abstract review,finally,19 articles in English language with 1326 participants were included through strict inclusion and exclusion criteria.The results revealed that mindfulness meditation had a signifi-cantly larger effect on alleviating military-related PTSD symptoms compared with control conditions,such as treatment as usual,present-centered group therapy and PTSD health education(standardized mean difference(SMD)=-0.33;95％CI[-0.45,-0.21];p＜0.0001).Mindfulness interventions with different control conditions(active or non-active control,SMD =-0.33,95％CI[-0.46,-0.19];SMD =-0.49,95％CI[-0.88,-0.10],respectively),formats of delivery(group-based or individual-based,SMD =-0.30,95％CI[-0.42,-0.17],SMD =-0.49,95％CI[-0.90,-0.08],respectively)and intervention durations(short-term or standard duration.SMD =-0.27,95％CI[-0.46.-0.08],SMD =-0.40,95％CI[-0.58,-0.21],respectively)were equally effective in improving military-related PTSD symptoms.Conclusion:Findings from this meta-analysis consolidate the efficacy and feasibility of mindfulness meditation in the treatment of military-related PTSD.Further evidence with higher quality and more rigorous design is needed in the future.
      原文链接:
    • NETL
    • NSTL
    • 维普
    • 万方数据

    The impact of the COVID-19 pandemic on the mental health of young people:A comparison between China and the United Kingdom

    Ming-Bo LiuGéraldine DufourZhuo-Er SunJulieta Galante...
    231-236页
    查看更多>>摘要：Purpose:As COVID-19 spreads globally and affects people's health,there are concerns that the pandemic and control policies may have psychological effects on young people(age from 17 to 35 years).This psychological impact might vary in different countries,and thus we compared the prevalence of self-reported psychological distress,loneliness and posttraumatic stress symptoms(PTSS)among young people in the United Kingdom(UK)and China at the beginning of the COVID-19 pandemic.Methods:Data of this study came from two sources.One source was the first wave of COVID-19 study in Understanding Society,a special wave of the UK household longitudinal study,which provided the high-quality,national-wide representative panel data.The sample comprised 1054 young people.The other source was an online survey on the mental health of 1003 young people from Shanghai,a highly developed area in China.The questionnaire included questions on the prevalence of common mental disorders(cut-off score≥4),loneliness and potential PTSS(cut-off≥33).Univariable analyses were conducted to test the differences in the self-reported prevalence of psychological distress and loneliness between the two groups.Multivariable logistic regression analyses were run to explore the predictors of psychological distress and loneliness among all the young people from England and Shanghai.Results:Among the samples with self-reported psychological distress,the UK sample accounted for 34.4％(n=1054)and the Chinese sample accounted for 14.1％(n=1003).The difference between the two groups was statistically significant(p＜0.001).Additionally,57.1％of people in the UK and 46.7％in China reported that they sometimes or often felt lonely,of which the difference is statistically significant(p＜0.001).Regression analysis of the entire samples showed that nationality,gender,psychotherapy and loneliness were significant predictors of 12-item General Health Questionnaire scores,while the vari-ables of age and living alone were not.Significant predictors of self-reported loneliness were the na-tionality,gender,age,living alone and psychotherapy.In China,123(12.3％)young people,49 men(11.3％)and 74 women(13.0％),met the criteria of PTSS symptoms(cut-off scores≥33).These scores were only collected in China.Conclusion:This evidence suggests that mental health and loneliness reported by young people were lower in China than that in the UK during the studied period.More research is needed to understand these differences.If the differential negative psychological impacts are confirmed,country-specific measures of prevention and intervention should be adopted to improve the mental health of young people under the ongoing impact of the pandemic.
      原文链接:
    • NETL
    • NSTL
    • 维普
    • 万方数据

    The impact of serving in disaster relief among volunteers in Malaysia

    Hoi Yen ChenChe An AhmadKhatijah Lim Abdullah
    237-248页
    查看更多>>摘要：Purpose:Malaysian disaster relief volunteers have a long and proud history of participating in relief missions within and outside the country.Despite of a plethora of researches into the various areas of disaster relief,there has been a little scholarly activity looking into the experiences of the medical volunteers worldwide and even less research on the experiences of the relief volunteers in Malaysia.Therefore,the purpose of this study is to identify the effect of disaster relief works on volunteers in Malaysia.Methods:This is a non-experimental cross-sectional design study,which was conducted using survey questionnaire to examine the incidence of burnout,posttraumatic stress disorder(PTSD)symptoms and the quality of life(QOL)among the disaster relief volunteers.And the study also examined the socio-demographic variables of the participants.In addition,the association between the sociodemographic variable and the preferred coping strategies was also investigated through self-reporting checklist.Results:The findings of this study revealed that 90.9％volunteers(n = 312)experienced some levels of recurring stress throughout their lives,which led to burnout.Also,96.8％(n = 332)of the participants were categorized as having at least some symptoms of PTSD.However,self-reporting QOL measurements indicated that the participants are,in general,satisfied with their lives.Significant associations between the incidence of burnout,incidence of PTSD and QOL were identified.Both positive coping measures and behavioral or avoidant coping measures were also identified.Furthermore,a number of socio-demographic factors were also seen to interact significantly with burnout,PTSD and QOL.Conclusion:This study provides some insights into the psychological challenges of disaster relief vol-unteers in Malaysia,and this impact can last a long time after the volunteers return to their hometowns.Several recommendations including practice development,policy and research were discussed in the study.
      原文链接:
    • NETL
    • NSTL
    • 维普
    • 万方数据

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      原文链接:
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