RENIN INHIBITORS

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欧洲专利局

外文摘要：Disclosed are compounds according to Formula I:wherein the variables are defined herein. Such compounds are can bind aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity.Also described herein are methods of antagonizing aspartic protease inhibitors in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound according to Formula I.

申请号：

US20090225987

申请日：

2009-05-18

公开日：

2009-11-05

IPC分类：

A61K-31/5377、A61K-31/40、A61K-31/445、A61K-31/4545、A61P-9/12、C07D-207/14、C07D-211/32、C07D-401/10、C07D-413/06、A61K-31/40、A61K-31/445、A61K-31/4523、A61K-31/5375、A61P-9/00、C07D-207/00、C07D-211/00、C07D-401/00、C07D-413/00

申请人：

Baldwin, John J.BaldwinJohn J.;Claremon, David A.ClaremonDavid A.;Tice, Colin M.TiceColin M.;Cacatian, SalvacionCacatianSalvacion;Dillard, Lawrence W.DillardLawrence W.;Ishchenko, Alexey V.IshchenkoAlexey V.;Yuan, JingYuanJing;Xu, ZhenrongXuZhenrong;McGeeh

发明人：

Baldwin, John J.、Claremon, David A.、Tice, Colin M.、Cacatian, Salvacion、Dillard, Lawrence W.、Ishchenko, Alexey V.、Yuan, Jing、Xu, Zhenrong、McGeehan, Gerard、Zhao, Wei、Simpson, Robert D.、Singh, Suresh B.、Flaherty, Patrick T.、Kallander, Lara S.、Leach, Colin A.、Lawhorn, Brian、Lu, Qing、Terrell, Lamont R.、Ghavini-Alagha, Bahman、Zhang, Jing、Ghirlanda, Damiano、Hou, Xiaoping、Semus, Simon

国别省市代码：

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