Synthesis of 1,4-Dioxaspiro[4.5]decane-8,8-diyldimethanol
The target compound 1,4-dioxaspirodecane[4.5]-8,8-dimethanol was prepared through cyclization,decar-boxylation,condensation and reduction by using dimethyl malonate and ethyl acrylate as raw materials,the total yield of four-step reaction was 60.6％,raction parameters of each step was studied and the target compound was characterized by confirmed by MS and 1H NMR. The raw materials are readily available,the yield is high,and the process is simple.
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