Study on 6-Bromoquinoline Analysis and Detection Method
Establish a high-performance liquid chromatography detection method for 6-bromoquinoline,prioritizing C18 column as the separation column. Select trifluoroacetic acid acetonitrile solution and trifluoroacetic acid aqueous solution as mobile phases,and perform gradient elution. The detector is an ultraviolet detector with a detection wavelength of 240 nm. Using a Karl Fischer moisture analyzer,study the moisture content of 6-bromoquinoline. Finally,a validation study was conducted on the accuracy and precision of the detection method.