A mono C-H bond activation derivative (C8H6NCH2)-C2HB10H10 was synthesized by the direct addition reaction of propargyl indole with borane.It was characterized by NMR spectroscopy,high reso-lution mass spectrum and single crystal X-ray diffraction.The structure showed the compound was crys-tallized in orthorhombic crystal system,P212121 space group.In order to further expand the application,indole skeleton was modified at 3-position with tetrahydropyrrolyl methylene to synthesize compound[3-(C4H8NCH2)C8H5NCH2]-C2HB10H10 by Mannich reaction,with the crystal structure in monoclinic crystal system,C2/c space group.This synthetic method succeeded in introducing electron-rich indolyl to electron-deficient carborane skeleton,and provided a new approach for the synthesis of novel boron clus-ter compounds.
o-Carborane1,3-disubstituted indolefunctionalization of C-Hsynthesis