Research progress on detection methods and vaccines for fowl adenovirus serotype 4
Fowl adenovirus serotype 4(FAdV-4)is characterized by infecting broilers aged 3-6 weeks,mainly causing pericardial effusion-hepatitis syndrome.It has a wide range of transmissions,causing significant losses to the poultry industry.There are 12 serotypes of fowl adenovirus,and due to the numerous serotypes,it brings certain difficulties to the diagnosis and prevention of fowl adenovirus serotype 4.This article reviewd the molecular biology detection methods(polymerase chain reaction,real-time fluorescence quantitative PCR,and loop-mediated isothermal amplification),serological detection methods,and other detection techniques,as well as the latest research progress in inactivated vaccines,attenuated vaccines,genetically engineered vaccines,and biological products for fowl adenovirus serotype 4.It provided a reference for the detection and vaccine research of fowl adenovirus serotype 4.
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