Objective:To explore the effective strategies to reduce the scrap rate of blood products due to positive irregular antibodies and direct anti-human globulin tests in Yancheng area, and improve the safety of clinical blood transfusion. Methods:Analyze the situation of hospital blood withdrawal due to irregular antibody positive or direct antibody positive cases in Yancheng area from January 2019 to December 2022. Conduct irregular antibody or direct antibody testing for blood withdrawal, and combine data from unpaid blood donors for research and analysis. Results:A total of 221 blood products returned to our station by the hospital due to positive irregular antibodies or direct antibodies. After confirmation, 117 cases were positive for irregular antibodies, 74 cases were positive for direct antibodies, and 4 cases were both; The MN system accounted for the highest proportion of 38.02％ (46/121), in irregular antibody positive samples. The positive rates of irregular antibodies and direct antibodies in women were higher than those in men, with a statistically significant difference (P<0.05); In the ABO system blood types, there was a statistically significant difference in the positive rates of irregular antibodies among the four blood types (P<0.05), while there was nothing in the positive rates of direct antibodies (P>0.05).Comparing different months, the positive rate of irregular antibodies in winter is higher than that in summer, while the positive rate of direct antibodies in summer is higher than that in winter. Conclusion: To reduce the scrap rate of irregular antibodies and direct antibody positive blood products in our station and improve the efficiency of clinical blood transfusion, we should first recruit accurate blood donors, and then conduct irregular antibody and direct antibody screening among the unpaid blood donors.
维普
万方数据
