安徽医专学报2024,Vol.23Issue(1) :42-45.DOI:10.20072/j.cnki.issn2097-0196.2024.01.014

清肝利胆法配合胆囊穿刺引流治疗高龄重症急性胆囊炎临床研究

Clinical study on clearing liver and gallbladder puncture drainage for advanced severe acute cholecystitis

黄敬宇 石秀全 陈杰 朱杰 杨郑 强泽好 高翔
安徽医专学报2024,Vol.23Issue(1) :42-45.DOI:10.20072/j.cnki.issn2097-0196.2024.01.014

清肝利胆法配合胆囊穿刺引流治疗高龄重症急性胆囊炎临床研究

Clinical study on clearing liver and gallbladder puncture drainage for advanced severe acute cholecystitis

黄敬宇 1石秀全 1陈杰 1朱杰 1杨郑 1强泽好 1高翔2
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作者信息

  • 1. 颍上县人民医院普外科 安徽颍上 236200
  • 2. 安徽中医药大学第二附属医院普外科 安徽合肥 230000
  • 折叠

摘要

目的:探讨给予高龄重症急性胆囊炎患者胆囊穿刺引流+清肝利胆法治疗的效果.方法:选取医院收治的60例高龄重症急性胆囊炎患者,经随机数表法分为两组.对照组(30例)患者进行超声引导下经皮肝胆囊穿刺置管引流术(PTGBD)治疗,治疗组(30例)患者进行PTGBD+清肝利胆法治疗.观察患者相关血清指标、炎性因子水平变化情况及临床症状体征改善、总疗效.结果:两组经过治疗后,治疗组患者WBC、ALT及GGT水平相比治疗前、对照组均明显更低,差异有统计学意义(P<0.05);治疗组患者CRP、IL-6及TNF-α水平均低于治疗前,同时低于对照组,差异有统计学意义(P<0.05);治疗后,治疗组患者各项中医症候评分相比对照组均更低,差异有统计学意义(P<0.05);两组患者临床治疗总有效率分别为73.33%、90.00%,治疗组总有效率明显更高,差异有统计学意义(P<0.05).结论:选用PTGBD+清肝利胆法的中西医结合方案,给予高龄重症急性胆囊炎患者治疗,能够更好地改善患者相关血清指标、炎性因子水平,减少患者不适情况,提高患者临床症状和体征的改善效果,获得更理想总体疗效.

Abstract

Objective:To explore the effect of gallbladder puncture and drainage 60 clear liver bile in elderly patients with severe acute cholecystitis.Methods:elderly patients with severe acute cholecystitis admitted were grouped by random numbers.The control group(30 patients)were treated with ultrasound-guided percutaneous catheterization(PTGBD)by transliver and gallbladder puncture,and PTGBD+clear liver and gallbladder therapy in the patients(30 patients).Changes in relevant serum indicators,inflammatory factors,clinical symptoms and signs,and overall efficacy were observed.Result:After the treatment,The levels of WBC,ALT and GGT were significantly lower compared with the pre-treatment and control groups,The difference was statistically significant(P<0.05);The levels of CRP,IL-6 and TNF-αin the treatment group were lower than before treatment,Also lower than that in the control group,The difference was statistically significant(P<0.05);post-treatment,The various TCM syndrome scores in the treatment group were lower compared with the control group,The difference was statistically significant(P<0.05);The total clinical response rate of the two groups was 73.33% and 90.00%,respectively,Overall response rate was significantly higher in the treatment group,The difference was statistically significant(P<0.05).Conclusion:PTGBD+combined traditional Chinese and western medicine for severe acute cholecystitis patients can improve the relevant serum indexes and inflammatory factors,improve the improvement effect of clinical symptoms and signs,and obtain a more ideal overall effect.

关键词

急性胆囊炎/重症/高龄/经皮经肝胆囊穿刺置管引流术/清肝利胆法

Key words

acute cholecystitis/severe/advanced age/percutaneous transliver gallbladder puncture and drainage/clear liver and gallbladder method

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基金项目

安徽省中医药局中医药传承创新科研项目(2020ccyb29)

阜阳市卫生健康委科研项目(FY2021-091)

出版年

2024
安徽医专学报
安徽医学高等专科学校

安徽医专学报

影响因子:0.441
ISSN:2097-0196
参考文献量12
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