Objective:To analyze the correlation and clinical significance of serum hsTnI, PTH and plasma BNP levels with the degree of hypertension in patients with stage 5 chronic kidney disease (CKD). Method:Eighty-five patients with CKD stage 5 and different degrees of hypertension were selected as the study group and 30 healthy subjects admitted to the hospital for physical examination at the same time as the control group, of which 17 were in hypertension grade I (group A), 26 were in grade Ⅱ(group B) and 42 were in grade Ⅲ(group C). Then the differences in hsTnI, PTH and BNP levels of the three groups were compared with those of the control group, and their correlation with hypertension grade was analysed.Result:The levels of serum hsTnI, PTH and plasma BNP in groups A, B and C were significantly higher than those in the control group (P<0.05). By Spearman correlation analysis, the levels of hsTnI, PTH and BNP were positively correlated with the grade of hypertension (P<0.001). Conclusion:The levels of serum hsTnI, PTH and plasma BNP are strongly correlated with the hypertension of CKD stage 5 patients, which plays an important role in the clinical evaluation of CKD stage 5 patients with hypertension.
维普
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