Objective:To explore the impact of situational simulation teaching method on the clinical decision-making and emergency response skills of medical students during their anesthesiology internship.Methods:A team of simulation instructors, comprising anesthesiologists from our hospital with substantial clinical expertise who also hold clinical professorships more than five yeas at Nanjing Medical University, was established. Medical students studing in anesthesiology department in 2022 were randomly assigned to either a control group, where they received traditional lectures on anesthesia crisis management, or an intervention group, where they were engaged in immersive simulation training for anesthesia crisis scenarios. We used questionnaire surveys and exam scores to measure the outcomes.Results:Students who underwent immersive simulation training for anesthesia crisis scenarios reported a higher level of satisfaction. Additionally, their post-training examination scores and end-of-year theoretical examination scores were significantly better than those of the control group.Conclusions:By enhancing simulation facilities, refining curriculum design, and integrating an "online-offline" approach to simulate anesthesia crisis scenarios thoroughly, our immersive training program has effectively bolstered the clinical decision-making and emergency response skills of medical students in handling crises. The findings from our study highlight the pressing need for a significant transformation of anesthesia education, from its content to its delivery method.