Objective:To investigate the possible correlation between social cognition and stigma in patients with schizophrenia.Methods:74 SCH patients and 43 normal controls were collected. Conduct social cognitive assessment on all subjects and assess the sense of stigma in SCH patients.Result: The interpersonal response index of SCH patients was lower than that of normal people in all dimensions except personal pain(P<0.05). The scores of all dimensions of the Toronto Alexithymia Scale were higher than those of normal people (P<0.05) . The correct rate of face emotion recognition in all dimensions was lower than that of normal people(P<0.05) , and the reaction time of face emotion recognition was longer than that of normal people(P<0.05). Pearson correlation analysis of 74 SCH patients showed that opinion selection was positively correlated with demeaning discrimination and negatively correlated with challenge in interpersonal response (P<0.05). Compassionate care was negatively correlated with challenge and misunderstanding(P<0.05), personal pain was negatively correlated with misunderstanding, disparage-discrimination, withdrawal and difference/shame in stigma (P<0.05). Imagination was positively correlated with demeaning and discrimination(P<0.05). Difficulty in describing and recognizing one's own emotions was negatively correlated with difference/shame (P<0.05). Extroversion thinking was negatively correlated with demeaning discrimination, withdrawal, difference/shame (P<0.05).The accuracy of positive and neutral face recognition was positively correlated with dissimilarity/shame (P<0.05).Conclusion:SCH patients are impaired in all dimensions of social cognition, and the correlation analysis results suggest that social cognition is positively correlated with stigma.