Objective:To exPlore the intravenous thrombolysis effect and its imPact on hemorheology of the combination of quercetin and asPirin in the treatment of elderly ACI(acute cerebral infarction).Method:80 elderly ACI Patients admitted to hosPital were selected as samPles.They were randomly divided into two grouPs using a random number table method.The control grouP was treated with asPirin,while the observation grouP was treated with a combination of quercetin and asPirin.Both grouPs were treated for 2 weeks.ComPare the theraPeutic effects of two grouPs.Result:After 2 weeks of treatment,the modified Rankin Scale(mRs)and National Institutes of Health Stroke Scale(NIHSS)scores of the observation grouP were lower than those of the control grouP,and Patients with mRs grading 0-2 were higher than that the control grouP(P<0.05).After 2 weeks of treatment,the levels of ET-1(endothelin-1),TSP-1,and sTLT-1 in the observation grouP were lower than those in the control grouP,while NO(nitric oxide)was higher than that in the control grouP(P<0.05).After 2 weeks of treatment,the Plasma viscosity,high shear viscosity,and low shear viscosity of the observation grouP were lower than those of the control grouP(P<0.05).Conclusion:The combination of quercetin and asPirin has a good intravenous thrombolysis effect and an ideal Prognosis in the treatment of elderly ACI.