首页|中性粒细胞与淋巴细胞比值与中枢免疫性疾病预后研究进展(综述)

中性粒细胞与淋巴细胞比值与中枢免疫性疾病预后研究进展(综述)

Advances in neutrophil to lymphocyte ratio and prognosis of central immune diseases

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中性粒细胞与淋巴细胞计数的比值(NLR)是全血细胞计数衍生的、相对简单的参数.NLR与全身炎症和慢性疾病之间的关联已在许多相关研究中得到证实,并被证明是高度敏感的生物标志物,而且正在成为几种疾病的独立预后因素.NLR反应炎症和免疫调节两个方面的平衡状态,而炎症和免疫反应与中枢神经系统免疫性疾病密切相关.目前NLR等生物标志物在中枢神经系统免疫性疾病中的研究相对有限.该文就NLR在中枢神经系统免疫性疾病中的临床应用进展做一回顾,并对NLR在该类疾病预后评估中的未来发展方向及应用前景进行展望,希望为临床诊疗及疾病预后等方面提供参考.
The ratio of neutrophil to lymphocyte count(NLR)is a relatively simple parameter derived from the complete blood count.The association between NLR and systemic inflammation and chronic disease has been demonstrated in many related studies and is proving to be a highly sensitive biomarker,and is emerging as an independent prognostic factor for several diseases.NLR reflects the balance between inflammation and immune regulation,and inflammation and immune response are closely related to central nervous system immune diseases.At present,the research of biomarkers such as NLR in central nervous system immune diseases is relatively limited.In this paper,the clinical application of NLR in central nervous system immune diseases is reviewed,and the future development direction and application prospect of NLR in the prognosis evaluation of these diseases are prospeced.Hope to provide reference for clinical diagnosis,treatment and prognosis of the disease.

neutrophillymphocyteratio of neutrophil to lymphocyte countimmune diseases of central nervous system

宋彬、朱凌、刘永凤、王伟、舒山、吴桐、赵婷婷、韩永升

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安徽中医药大学神经病学研究所附属医院 安徽合肥 230061

中性粒细胞 淋巴细胞 中性粒细胞与淋巴细胞计数的比值 中枢神经系统免疫性疾病

安徽省自然科学基金安徽中医药大学临床科研基金重点项目(2020)

1908085QH3442020sjzd11

2024

安徽医专学报
安徽医学高等专科学校

安徽医专学报

影响因子:0.441
ISSN:2097-0196
年,卷(期):2024.23(2)
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