Objective:To analyze the diagnostic accuracy and true negative rate of CT-guided percutaneous biopsy of small pulmonary nodules(≤ 20 mm).Method:A retrospective analysis was conducted on the success rate,diagnostic accuracy,and true negative data of 120 patients with pulmonary nodules who underwent CT guided biopsy in our center.Re sult:The success rate was 100％,and the biopsy results of 120 lung nodules included malignant tumors(n=67),suspected malignant tumors(n=4),specific benign lesions(n=8),and non-specific benign lesions(n=41)The final diagnosis includes malignant(n=87),benign(n=31),and non diagnostic lesions(n=2),The sensitivity,specificity,and diagnostic accuracy were 81.6％,100％,and 87.9％,respectively.Based on Cox regression analysis,the significant independent predictor of true negativity is chronic inflammation with fibrosis.Conclusion:CT guided needle biopsy of pulmonary nodules has high diagnostic accuracy,and chronic inflammation with fibrosis can predict true negative results.
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