摘要
目的:探讨CT引导下对肺小结节(≤20mm)穿刺活检的诊断准确性和真阴性.方法:回顾性分析医院影像中心120例肺部小结节患者接受CT引导下的穿刺活检成功率、诊断准确性和真阴性的数据.结果:穿刺活检成功率100％,120个肺结节的穿刺活检结果包括恶性肿瘤(67例)、疑似恶性肿瘤(4例)、特异性良性病变(8例)和非特异性良性病变(41例);最终诊断包括恶性(87例)、良性(31例)和非诊断性病变(2例);敏感性、特异性和诊断准确率分别为81.6％、100％和87.9％.基于Cox回归分析,真正阴性的显著独立预测因素是慢性炎症伴纤维增生.结论:CT引导下肺小结节穿刺活检具有较高的诊断准确性,慢性炎症伴纤维增生可预测真正的阴性结果.
Abstract
Objective:To analyze the diagnostic accuracy and true negative rate of CT-guided percutaneous biopsy of small pulmonary nodules(≤ 20 mm).Method:A retrospective analysis was conducted on the success rate,diagnostic accuracy,and true negative data of 120 patients with pulmonary nodules who underwent CT guided biopsy in our center.Re sult:The success rate was 100％,and the biopsy results of 120 lung nodules included malignant tumors(n=67),suspected malignant tumors(n=4),specific benign lesions(n=8),and non-specific benign lesions(n=41)The final diagnosis includes malignant(n=87),benign(n=31),and non diagnostic lesions(n=2),The sensitivity,specificity,and diagnostic accuracy were 81.6％,100％,and 87.9％,respectively.Based on Cox regression analysis,the significant independent predictor of true negativity is chronic inflammation with fibrosis.Conclusion:CT guided needle biopsy of pulmonary nodules has high diagnostic accuracy,and chronic inflammation with fibrosis can predict true negative results.
NETL
NSTL
万方数据