摘要
目的:探讨血红蛋白、白蛋白、淋巴细胞及血小板(HALP)评分联合尿素氮对大面积烧伤患者的预后的预测及临床意义.方法:收集分析112例大面积烧伤患者的临床数据,依据受伤后90d的观察结局将其分为幸存组(96例)与死亡组(16例);收集患者的年龄、性别、住院时间等基础信息及入院第3天的白蛋白、血小板、尿素氮、血红蛋白等相关实验室指标.采用单因素及多因素Logistic回归分析影响预后的指标;HALP评分、尿素氮及其联合检测的预测价值通过受试者工作特征(ROC)曲线分析.结果:死亡组患者的HALP评分及尿素氮水平均高于幸存组(P＜0.05);ROC曲线结果显示:HALP评分、尿素氮及联合检测的AUC分别为0.779、0.757、0.874.结论:HALP评分、尿素氮对预测大面积烧伤患者的预后具有良好的预测效能,且联合预测更高.
Abstract
Objective:To evaluate the prognostic value and clinical significance of the combined assessment of hemoglobin,albumin,lymphocytes,and platelets(HALP)score with blood urea nitrogen(BUN)in predicting the outcomes of patients with large-area burns.Methods:A total of 112 patients with large-area burns were included in the study.Based on the 90-day post-injury survival outcome,patients were categorized into a survival group(n=96)and a death group(n=16).Clinical data,including age,gender,length of hospital stay,and laboratory indicators(albumin,platelets,BUN,and hemoglobin)measured on the third day post-admission,were collected.Univariate and multivariate logistic regression analyses were performed to identify the prognostic factors.The predictive accuracy of the HALP score,BUN,and their combined use was assessed through receiver operating characteristic(ROC)curve analysis.Results:The HALP score and BUN levels in the death group were significantly higher than those in the survival group(P＜0.05).ROC curve analysis revealed that the AUC values for the HALP score,BUN,and their combination were 0.779,0.757,and 0.874,respectively.Conclusion:The HALP score and BUN are reliable indicators for predicting the prognosis of patients with large-area burns,and their combined use offers superior predictive performance.
维普
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