Objective:To evaluate the therapeutic impact of coronary intervention on hemodialysis patients suffering from coronary heart disease.Methods:A total of 70 individuals with chronic renal failure,undergoing regular hemodialysis,and diagnosed with coronary heart disease were randomly allocated into two groups,each comprising 35 participants.The control group received conventional medication,whereas the study group was subjected to coronary intervention.Key outcomes,including cardiac function parameters,serum NT-proBNP,inflammatory markers,renal function indicators,and the frequency of cardiovascular events,were compared between the two groups.Results:Post-treatment,the study group exhibited significantly higher LVEF values and lower LVEDV values compared to the control group(P<0.05).Additionally,the study group showed elevated IL-10 levels and reduced NT-proBNP,IL-1,and TNF-α levels relative to the control group(P<0.05).No significant changes in renal function parameters were observed between the two groups before and after treatment(P>0.05).Conclusion:For patients with chronic renal failure,continuous hemodialysis,and coronary heart disease,coronary intervention demonstrates superior clinical outcomes,enhances cardiac performance,and effectively modulates inflammatory markers and NT-proBNP levels,while maintaining high safety.