首页|老年血液透析患者认知衰弱现状及其影响因素分析

老年血液透析患者认知衰弱现状及其影响因素分析

Analysis of cognitive weakness and influencing factors in elderly hemodialysis patients

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目的:探讨老年血液透析患者认知衰弱现状及影响因素.方法:将医院收治的50例老年血液透析患者纳为研究对象,根据患者有无认知衰弱将其分为认知正常组(30例,MMSE<27分)、认知衰弱组(20例,MMSE≥27分),对两组患者进行问卷调查分析,并应用Logistic回归分析认知衰弱的影响因素.结果:认知正常组患者红细胞、血红蛋白、血小板、肌酐、总胆固醇、总蛋白、白蛋白、性别构成比与认知衰弱组比较,差异均无统计学意义(P>0.05),认知正常组患者年龄、血磷、白细胞、淋巴细胞、尿素氮、尿酸、甘油三酯、超敏C反应蛋白、CFAI评分、透析时间显著低于认知衰弱组(P<0.05),认知正常组患者血钙水平显著高于认知衰弱组(P<0.05).结论:年龄、血磷、白细胞、淋巴细胞、尿素氮、尿酸、甘油三酯、超敏C反应蛋白、血钙、透析时间、CFAI评分等因素都是老年血液透析患者认知衰弱的影响因素.
Objective:To analyze the status quo and influencing factors of cognitive frailty in elderly hemodialysis patients.Methods:Fifty elderly hemodialysis patients in hospital were included in the study.According to whether the patients had cognitive frailty,they were divided into cognitive normal group(30 cases,MMSE<27 points)and cognitive frailty group(20 cases,MMSE≥27 points).A questionnaire survey was conducted on the two groups of patients.The influencing factors of cognitive frailty were analyzed by Logistic regression.Result:There was no statistically significant difference in the gender composition ratio of red blood cells,hemoglobin,platelets,creatinine,total cholesterol,total protein,and albumin between the cognitively normal group and the cognitively impaired group(P>0.05).The age,blood phosphorus,white blood cells,lymphocytes,urea nitrogen,uric acid,triglycerides,high-sensitivity C-reactive protein,CFAI score,and dialysis time of the cognitively normal group were significantly lower than those of the cognitively impaired group(P<0.05),while the blood calcium of the cognitively normal group was significantly higher than that of the cognitively impaired group(P<0.05).Conclusion:Age,blood phosphorus,white blood cells,lymphocytes,urea nitrogen,uric acid,albumin,triglycerides,high-sensitivity C-reactive protein,blood calcium,dialysis time,CFAI score and other factors are all influencing factors of cognitive decline in elderly hemodialysis patients.

hemodialysiscognitive weaknessinfluencing factors

姚迟、杨晓娟

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合肥市第二人民医院肾内科 安徽 合肥 230000

血液透析 认知衰弱 影响因素

2024

安徽医专学报
安徽医学高等专科学校

安徽医专学报

影响因子:0.441
ISSN:2097-0196
年,卷(期):2024.23(6)