摘要
目的 探究安徽省人类精子库捐精志愿者的生活方式与精液质量关联性.方法 收集2021年1月-2023年12月在安徽省人类精子库捐精的1 222名志愿者的人口学特征及生活方式,分析其与精液质量的相关性.结果 单因素卡方分析表明非学生、频繁自慰者、禁欲时长、低运动频率、经常熬夜、吸烟、饮酒和短睡眠时长与精液参数异常有显著关联(P<0.05).多因素Logistic回归分析进一步指出,非学生身份、禁欲时长、缺乏充足睡眠与精液量异常相关;禁欲时长、运动频率、熬夜、吸烟和睡眠时长与精液浓度和精子活力异常显著相关(P<0.05).结论 精液质量与志愿者的生活方式(禁欲时间、熬夜、睡眠时间、吸烟、饮酒及运动频率)密切相关.
Abstract
Objective To examines the correlation between lifestyle factors and semen quality among sperm donors at Anhui human sperm bank.Methods Demographic and lifestyle data were collected from 1,222 volunteers who donated sperm between January 2021 and December 2023,and their association with semen quality was analyzed.Results Univariate chi-square analysis revealed significant associations between several lifestyle factors and abnor-mal semen parameters(P<0.05),including non-student status,frequent masturbation,short-term abstinence,low exercise frequency,frequent staying up late,smoking,drinking,and short sleep duration.Moreover,multiva-riate logistic regression analysis demonstrated that non-student status,longer abstinence time,and insufficient sleep were linked to abnormal semen volume.Additionally,abstinence time,exercise frequency,staying up late,smok-ing,and sleep duration were significantly correlated with abnormal semen concentration and sperm motility(P<0.05).Conclusion Analysis reveals a close relationship between semen quality and volunteers'lifestyles,inclu-ding factors such as abstinence time,staying up late,sleep duration,smoking,drinking,and exercise frequency.
基金项目
国家自然科学基金(82101682)
安徽省高校自然科学研究重点项目(2023AH053287)
安徽省转化医学研究院项目(2022zhyx-C33)
安徽医科大学基础与临床合作研究提升计划资助项目(2023xkjT036)