首页|冬瓜子中医药用药规律的数据挖掘

冬瓜子中医药用药规律的数据挖掘

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目的:从含冬瓜子的中药方剂中发掘冬瓜子的用药规律,可为冬瓜子的临床合理使用与开发奠定基础.方法:通过华柄数据、中医智库、普济方等数据库对冬瓜子的中药方剂进行检索.采用 EXCEL 2021,SPSS Modeler 18.0,SPSS Statistics 26,对各组分药物进行频率统计、关联规则分析、聚类分析.结果:共有 248 个含有冬瓜子的中药方剂被收录,其中在《中国药典》收录的有 319 种药物,与冬瓜子配伍次数最多的 10 个药是:薏苡仁、桃仁、甘草、金银花、芦根、牡丹皮、大黄、当归、茯苓和苦杏仁,主治疾病以肺系病类最多,核心药物组合为苇茎汤.结论:冬瓜子多与甘、苦、辛味,药性以温、寒、平,归肝经、肺经、胃经、脾经的药物配伍;常用于治疗肺系病类、脾系病类、肾系病类、生殖病类和皮肤黏膜病类疾病,与冬瓜子国内外现代药理研究结果基本一致.
Data Mining of Chinese Medicine Medication Pattern of Semen Benincasae
Objective:Discovering the medication rules of winter melon seeds from traditional Chinese medicine prescriptions containing winter melon seeds can lay a foundation for the clinical rational use and development of win-ter melon seeds.Methods:The traditional Chinese medicine prescriptions of winter melon seeds were searched through Huabing Data,Traditional Chinese Medicine Think Tank,Puji Fang and other databases.Use EXCEL 2021,SPSS Modeler 18.0,and SPSS Statistics 26 to conduct frequency statistics,association rule analysis,and cluster analysis on each component of the drug.Results:A total of 248 Chinese medicine prescriptions containing winter melon seeds were included,of which 319 were included in the"Chinese Pharmacopoeia".The 10 medicines with the most compatibility with winter melon seeds are:coix seed,peach kernel,licorice,honeysuckle,and reed root.,moutan bark,rhubarb,an-gelica root,poria cocos and bitter almond.The main diseases treated are lung diseases,and the core drug combination is Wei Jian Decoction.Conclusion:Winter melon seeds are mostly compatible with drugs that taste sweet,bitter,and pungent,and have warm,cold,and neutral properties,and belong to the liver,lung,stomach,and spleen meridians;they are often used to treat lung diseases,spleen diseases,and kidney diseases.Systemic diseases,reproductive diseases and skin and mucosal diseases are basically consistent with the results of modern pharmacological research on winter melon seeds at home and abroad.

Winter melon seedsTraditional Chinese medicineData miningFrequency statisticsAssociation rulesCluster analysis

杨钧涵、孙婉萍、谢明

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辽宁中医药大学药学院 辽宁大连 116600

冬瓜子 中医药 数据挖掘 频次统计 关联规则 聚类分析

国家青年自然科学基金中医药事业传承与发展中央直达补助专项辽宁省教育厅重点项目辽宁中医药大学科学自然基金项目

82204629财社[2022]63号L2020672021LZY014

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(1)
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