首页|度洛西汀联合黄连温胆汤对持续性姿势知觉性头晕的临床疗效研究

度洛西汀联合黄连温胆汤对持续性姿势知觉性头晕的临床疗效研究

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目的:观察在度洛西汀基础上联合使用黄连温胆汤,研究其对痰浊中阻型持续性姿势知觉性头晕的临床疗效.方法:选取 2021 年 6 月—2023 年 3 月就诊的持续性姿势知觉性头晕的患者,其中共有 40 例患者为痰浊中阻证.随机分成对照组、观察组,在对照组患者群体中,提供度洛西汀口服治疗方案,观察组患者则在对照组的基础上使用黄连温胆汤.在持续 4 周治疗后,分析 2 组在治疗前后分数,判断数据是否具备统计学意义.结果:在持续 4 周的疗程后,患者的HAMA、HAMD、DHI分数均出现明显的下滑;从DHI、HAMA评分上看,观察组和对照组的分数相比前者更低,差异均有统计学意义.从HAMD评分结果看,2 组数据无明显差异;在安全性指标方面 2 组无明显差异.结论:黄连温胆汤联合度洛西汀能有效改善患者临床症状,使患者头晕、焦虑、抑郁等情况得到缓解;黄连温胆汤在头晕、焦虑等临床症状效果佳,在抑郁等临床症状效果不明显,临床运用黄连温胆汤不良反应少.
A study on the Clinical Efficacy of Duloxetine Combined with Huanglian Wendan Tang in the Treatment of Persistent Postural Perceptual Dizziness
Objective:To observe the combined use of Huanglian Wendan Decoction on the basis of Duloxetine and study its clinical efficacy in treating persistent postural dizziness with phlegm turbidity and moderate obstruc-tion.Methods:Patients with persistent postural dizziness who presented to the hospital from June 2021 to March 2023 were selected.A total of 40 patients had the syndrome of phlegm turbidity and obstruction.The patients were randomly divided into a control group and an observation group.Patients in the control group were provided with an oral treat-ment regimen of duloxetine,while patients in the observation group were given Huanglian Wendan Decoction on the basis of the control group.After 4 weeks of treatment,the pre-and post-treatment scores of the 2 groups were analyzed to determine whether the data were statistically significant.Results:After a 4-week course of treatment,the patients'HAMA,HAMD,and DHI scores all declined significantly.From the DHI and HAMA scores,the scores of the observa-tion group and the control group were lower than the former,and the differences were statistically significant.signifi-cance.Judging from the HAMD score results,there was no significant difference in the data between the two groups;there was no significant difference in the safety indicators between the two groups.Conclusion:Huanglian Wendan Decoction combined with Duloxetine can effectively improve the clinical symptoms of patients and alleviate dizziness,anxiety,depression and other conditions;Huanglian Wendan Decoction has good effects on clinical symptoms such as dizziness and anxiety,and is effective on clinical symptoms such as depression.It is not obvious,and the clinical ap-plication of Huanglian Wendan Decoction has few adverse reactions.

Persistent postural dizzinessPhlegm obstructionHuanglian Wendan DecoctionDuloxetineScale

程万仁、曹昌军、王飞、郑应平、任超、陈季玮

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安徽省无为市中医医院 安徽芜湖 238300

持续性姿势知觉性头晕 痰浊中阻 黄连温胆汤 度洛西汀 量表

芜湖市卫生健康委课题

芜卫科教函[2021]9号

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(1)
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