Effect of Buqi Huoxue Tongluo Formula Combined with Dual Antiplatelet Therapy on the Changes of Serum Markers and Stent Restenosis after Cerebral Vascular Stenting
Effect of Buqi Huoxue Tongluo Formula Combined with Dual Antiplatelet Therapy on the Changes of Serum Markers and Stent Restenosis after Cerebral Vascular Stenting
Objective: To observe the effect of Buqi Huoxue Tongluo prescription combined with dual anti-drug drugs on serological changes and restenosis rate in patients with ischemic stroke who underwent stent implantation. Methods: 100 patients with cerebrovascular stent implantation who met the inclusion criteria were randomly divided into a control group and a treatment group, 50 cases in each group. Both groups were treated with aspirin (100 mg/d) plus Plavix (75 mg/d). On this basis, patients in the treatment group were given Buqi Huoxue Tongluo prescription for 6 months. The changes in inflammatory factors and platelet-related indicators and the restenosis rate of the 2 groups of patients before and after treatment were observed. Results: The differences in serum inflammatory factors and platelet-related indicators between the two groups of patients before and after treatment were statistically significant; the differ-ences between the groups were statistically significant. The restenosis rate in the treatment group was 10％, and that in the control group was 26％. The restenosis rate between the two groups was statistically significant. Conclusion: Buqi Huoxue Tongluo prescription combined with dual-antibody drugs is more effective than dual-antibody drug therapy alone in the treatment of patients with cerebral vascular stent implantation. It can reduce serum inflammatory factors, enhance anti-platelet aggregation, and reduce restenosis rate.
关键词
中医药/缺血性脑卒中/血清学/支架再狭窄
Key words
Traditional Chinese medicine/Ischemic stroke/Serology/Stent restenosis
维普
万方数据