Clinical Efficacy of Modified Sanwei Decoction in the Treatment of Non-motor Symptoms of Parkinson's Disease
Objective: To explore the clinical efficacy of Modified Sanwei Decoction in treating non-motor symptoms in patients with Parkinson's disease, in order to obtain better therapeutic effects and clinical experience. Methods: 50 patients with Parkinson's disease who met the criteria were selected and randomly divided into a control group and an experimental group, with 25 cases in each group. The control group was treated with dobaserazine tablets; the experi-mental group was treated with modified Sanwei decoction on this basis. , after one course of treatment, the daily non-motor symptoms in the new version of the World Movement Disorder Society Parkinson's Disease Scale (MDS-UPDRS) and the motor symptom scale in the two groups of patients were compared, including tremor, bradykinesia, cognitive function, A comprehensive assessment of twelve indicators including anxiety, depression, coughing when drinking water, nocturia, insomnia, drowsiness, constipation, fatigue, and drooling at the corners of the mouth. Results: Before treatment, there was no statistical difference or significance in the comprehensive scores of the selected indicators be-tween the two groups of patients (P>0.05); after treatment, the comprehensive scores of the patients in the experimental group were reduced compared with the scores in the control group, and there was a statistical difference and signifi-cance. significance (P<0.05). There is also a statistical difference and significance in the score decline rate between the two groups of patients (P<0.01). Conclusion: Modified Sanwei Decoction can improve non-motor symptoms and delay the progression of Parkinson's disease.
Modified Sanwei DecoctionParkinson's diseaseNon-motor symptomsTremor syndromeTraditional Chinese medicine therapyBrain-gut axis
万方数据
维普
