中医药临床杂志2024,Vol.36Issue(3) :548-551.DOI:10.16448/j.cjtcm.2024.0335

消风散加减联合复方黄柏液涂剂治疗血虚风燥型慢性肛周湿疹临床观察

Clinical Observation on the Treatment of Chronic Perianal Eczema by Applying Modified Xiaofeng Powder Orally Combined with Compound Huangbai Liquid

牛晨懿 卢灿省 孙玉敏 陈灿
中医药临床杂志2024,Vol.36Issue(3) :548-551.DOI:10.16448/j.cjtcm.2024.0335

消风散加减联合复方黄柏液涂剂治疗血虚风燥型慢性肛周湿疹临床观察

Clinical Observation on the Treatment of Chronic Perianal Eczema by Applying Modified Xiaofeng Powder Orally Combined with Compound Huangbai Liquid

牛晨懿 1卢灿省 2孙玉敏 1陈灿1
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作者信息

  • 1. 安徽中医药大学 安徽合肥 230038
  • 2. 安徽中医药大学第一附属医院 安徽合肥 230031
  • 折叠

摘要

目的:观察消风散加减联合复方黄柏液涂剂治疗血虚风燥型慢性肛周湿疹的临床疗效.方法:将64例已确诊的血虚风燥型慢性肛周湿疹患者,按随机数字表法分组,观察组、对照组各32例,观察组采用消风散加减联合复方黄柏液涂剂外敷治疗,对照组采用复方黄柏液涂剂外敷治疗,疗程为4周,比较2组的治疗效果.结果:观察组的治疗总有效率明显高于对照组,差异具有统计学意义(P<0.05).治疗后,观察组的肛周瘙痒、肛周渗液、皮损面积、皮损形态及白介素-4(IL-4)、肿瘤坏死因子-α(TNF-α)及血清总IgE水平均低于对照组,差异具有统计学意义(P<0.05).结论:消风散加减联合复方黄柏液涂剂治疗血虚风燥型慢性肛周湿疹有较好疗效.

Abstract

Objective: To observe the clinical efficacy of Xiaofeng Powder combined with Compound Phellodendron Cortex Liquid in the treatment of chronic perianal eczema of blood deficiency and wind dryness type. Methods: 64 con-firmed patients with chronic perianal eczema of blood deficiency and wind-dryness type were divided into groups ac-cording to the random number table method, with 32 cases in each observation group and control group. The observation group was treated with modified Xiaofeng Powder combined with compound Cortex Phellodendron liquid for external application. For treatment, the control group was treated with external application of Compound Cortex Phelloden-dron liquid lubricant. The course of treatment was 4 weeks. The therapeutic effects of the two groups were compared. Results: The total effective rate of treatment in the observation group was significantly higher than that in the control group, and the difference was statistically significant (P<0.05). After treatment, the perianal itching, perianal exuda-tion, skin lesion area, skin lesion morphology, interleukin-4 (IL-4), tumor necrosis factor-α (TNF-α) and serum total IgE levels in the observation group were all lower than In the control group, the difference was statistically significant (P<0.05). Conclusion: Modified Xiaofeng Powder combined with Compound Cortex Phellodendron Liquid Ointment has a good effect in the treatment of chronic perianal eczema of blood deficiency and wind dryness type.

关键词

消风散/复方黄柏液涂剂/慢性肛周湿疹

Key words

Xiaofeng powder/Compound Huangbai liquid liniment/Chronic perianal eczema

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基金项目

十二五国家临床重点专科建设项目(财社[2013]239号)

出版年

2024
中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
参考文献量13
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