首页|黄连解毒汤加减合金黄膏治疗早期肛周脓肿疗效及安全性分析

黄连解毒汤加减合金黄膏治疗早期肛周脓肿疗效及安全性分析

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目的:探讨黄连解毒汤加减合金黄膏治疗早期肛周脓肿疗效及安全性.方法:选取2020年1月—2023年3月就诊的早期肛周脓肿患者46例,随机分为对照组、观察组,均23例.对照组常规西医治疗,观察组在对照组的基础上增加黄连解毒汤加减合金黄膏治疗,5 d为1个疗程,连续2个疗程.统计2组患者临床疗效、症状及体征评分、炎性因子指标、疼痛程度、肿块面积、不良反应情况.结果:观察组患者临床有效率95.65% 高于对照组患者临床有效率82.61%,差异无统计学意义.治疗前,2组患者症状及体征评分比较无显著差异,治疗后,2组患者症状及体征评分均较治疗前明显下降,组间比较,观察组患者症状及体征评分均低于对照组患者;治疗前,2组患者炎性因子指标比较无显著差异,治疗后,2组患者炎性因子指标水平均较治疗前明显下降,组间比较,观察组患者炎性因子指标水平均低于对照组患者;治疗前,2组患者VAS评分、肿块面积比较无显著差异,治疗后,2组患者VAS评分、肿块面积均较治疗前明显下降,组间比较,观察组患者VAS评分、肿块面积均低于对照组患者,差异均有统计学意义;2组患者不良反应情况比较无显著差异.结论:黄连解毒汤加减合金黄膏治疗早期肛周脓肿患者,可显著缓解患者肛门疼痛,改善患者炎症状态,有效率较高,安全性良好.
Analysis on the Efficacy and Safety of Huanglian Jiedu Decoction plus Jiahe Jinhuang Paste in the Treatment of Early Perianal Abscess
Objective: To explore the efficacy and safety of Huanglian Jiedu Decoction plus Alloy Yellow Cream in the treatment of early perianal abscess. Methods: 46 patients with early perianal abscess who were diagnosed from Jan-uary 2020 to March 2023 were selected and randomly divided into a control group and an observation group, each with 23 cases. The control group was treated with conventional Western medicine, and the observation group was treated with Huanglian Jiedu Decoction plus Alloy Yellow Cream on the basis of the control group, with 5 days as one course of treatment, and 2 consecutive courses of treatment. The clinical efficacy, symptom and sign scores, inflammatory factor indicators, pain degree, tumor area, and adverse reactions of the 2 groups of patients were statistically analyzed. Re-sults: The clinical effective rate of the patients in the observation group was 95.65%, which was higher than the clinical effective rate of the patients in the control group, which was 82.61%. The difference was not statistically significant. Before treatment, there was no significant difference in the symptom and sign scores of the patients in the two groups. After treatment, the symptom and sign scores of the patients in the two groups were significantly lower than before treatment. In comparison between the groups, the symptom and sign scores of the patients in the observation group were lower than those of the control group; Before treatment, there was no significant difference in the inflammatory factor indexes between the two groups of patients. After treatment, the inflammatory factor index levels of the two groups of patients were significantly lower than before treatment. Comparing between groups, the inflammatory factor index levels of the patients in the observation group were lower than those of the control group. patients; before treatment, there was no significant difference in the VAS scores and mass area of the patients in the two groups. After treatment, the VAS scores and mass area of the patients in the two groups were significantly lower than before treatment. Compared between the groups, the VAS scores and mass area of the patients in the observation group were both lower. For patients in the control group, the differences were statistically significant; there was no significant difference in adverse reactions be-tween the 2 groups. Conclusion: Huanglian Jiedu Decoction plus Alloy Yellow Cream can significantly relieve anal pain and improve the inflammatory status of patients with early perianal abscess, with high efficiency and good safety.

Early perianal abscessModified Huanglian Jiedu DecoctionJinhuang OintmentClinical efficacySafety

高利伟、李新力、尹方方

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河南省开封市人民医院 河南开封 475000

早期肛周脓肿 黄连解毒汤加减 金黄膏 临床疗效 安全性

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(3)
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