Clinical Study of using Chinese Materia Medica Preparation after Pterygium Excision Combined with Limbal Stem Cell Transplantation
AIM To investigate the effect of Removing The Wind And The Benefit Loss Decoction(a traditional Chinese medicine) on ocular surface injury repair after pterygium operation. METHODS 100 cases of primary pte-rygium patients were randomly divided into observation group and control group. The control group received pterygium excision and limbal stem cell transplantation, and conventional eye drops were used for eye spotting after operation. On the basis of the control group, the observation group was treated with Removing The Wind And The Benefit Loss Decoction. Ultimately, we have also observed and compared the ocular pain scores(Visual Analogue Scale,VAS), ocular signs integrals(OSI), breaking up time(BUT) , corneal epithelial status scores(CESS) and the recurrence rate after treatments. RESULTS The VAS of the two groups on 1 d, 2 d and 1 wk after surgery was better than 6 h after surgery,and the differences were statistically significant (P＜0.05). The OSI on 2 d and 1 wk after surgery was better than 1 d after surgery, with statistical significance (P＜0.05). The VAS and OSI of observation group was better than control group, the differences were statistically significant (P＜0.05). The BUT and CESS of the observation group were better than those of the control group 1 wk after surgery (P＜0.05).The recurrence rate in the observation group was lower than that in the control group at 6 mth after surgery (P＜0.05). CONCLUSIONS It has a positive effect on promoting ocular surface reconstruction after surgery that use Removing The Wind And The Benefit Loss Decoction combined with excision and limbal stem cell transplantation to remedy the pterygium.
pterygiumcorneal limbal stem cell transplantationremoving the wind and the benefit loss decoction
万方数据
维普
