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储浩然应用加味温胆汤治疗胃食管反流病经验

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胃食管反流病(gastroesophageal reflux disease,GERD)属中医"吐酸""梅核气""胃痛""胸痛""呕吐"等范畴,是胃内容物反流至食管,引起烧心、反酸和反胃等症状且反复发作的一种常见的消化道慢性疾病,其发病率逐年增高,严重影响人们的身心健康.储浩然教授从事临床及基础研究30余年,擅长治疗消化系统疾病,他认为GERD的发病之本为脾胃虚弱,痰湿中阻为其重要病理因素,胆胃不和为其临床常见证型.脾胃虚弱则脾升胃降功能失常,尤以胃失和降为主;脾升胃降功能失常,中焦失衡,则水液代谢失常,痰湿聚集,阻碍中气,则脾陷胃逆;脾胃虚则土壅木郁,肝病下陷而胆病上逆,胆汁随胃气上逆而致胸骨后烧灼不适感、吐酸、嗳气诸症.故胃食管反流病的治疗上以和胃降逆,化痰理气为原则,以健脾胃复运纳、调中焦祛痰湿、和土木理气机为法.作者通过整理研究储浩然教授大量的原始医案,总结储浩然教授运用加味温胆汤治疗GERD的临床经验,并举验案一则为佐证,为临床治疗提供借鉴参考.
Clinical Experience of Chu Haoran in Treating with Modified wendan Decoction
Gastroesophageal reflux disease (GERD) is a prevalent chronic disorder of the digestive tract, falling under TCM categories such as "acid regurgitation," "plum qi," "stomachache," "chest pain," and "vomiting." Its incidence has been steadily increasing over the years, significantly impacting individuals' physical and mental well-being. Professor Chu Hao-ran has dedicated over 30 years to clinical and fundamental research, specializing in the treatment of gastrointestinal diseases. He posits that the pathogenesis of GERD lies in spleen and stomach weakness, with phlegm-dampness obstruction being a crucial pathological factor. Additionally, disharmony between bile and stomach commonly manifests clinically. Spleen-stomach weakness leads to impaired upward movement of spleen en-ergy and downward movement of stomach energy, particularly imbalancing the stomach function. Dysfunction in spleen ascending and stomach descending disrupts middle jiao equilibrium, resulting in water-fluid metabolism disorders along with phlegm-dampness accumulation that obstructs qi flow while causing inverse movements of spleen-stomach functions. Deficiency in spleen-stomach function leads to stagnation within soil-wood elements; liver depression affects bile circulation while reversing its normal flow with gastric qi. This ultimately results in discomfort characterized by burning sensation behind sternum, acid regurgitation, and belching. Therefore, treatment for gastroesophageal reflux disease focuses on reducing gastric refluxion while resolving phlegm accumulation through regulating qi flow. Strength-ening spleen-stomach function restores transportation and absorption capabilities while balancing middle jiao functions to eliminate phlegm-dampness obstruction alongside regulating overall qi mechanism. This paper extensively collects original medical cases from Professor Chu Hao-ran's practice for studying purposes. It summarizes his clinical expe-rience regarding GERD treatment using Jiawei

gastroesophageal reflux diseaseModified wendan Decoctionclinical experienceChu Haoran

马文黎、储浩然、邹玲、韩啸宇、方明

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安徽中医药大学 安徽合肥 230038

安徽中医药大学第二附属医院 安徽合肥 230061

安徽省中医药科学院针灸临床研究所 安徽合肥 230038

安徽省针灸临床医学研究中心 安徽合肥 230061

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胃食管反流病 加味温胆汤 临床经验 储浩然

全国名老中医药专家传承工作室建设项目(2022)安徽省中医药领军人才项目

国中医药人教发[2021]75号中医药发展秘[2018]23号

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(4)
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