首页|针刺疗法改善冻胚移植临床妊娠结局的回顾性研究

针刺疗法改善冻胚移植临床妊娠结局的回顾性研究

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目的:探索针刺疗法对体外受精-胚胎移植过程中行冻胚移植妊娠结局的影响.研究内容:回顾性分析2019年1月—2021年12月生殖中心行冷冻解冻胚胎移植的患者资料,按照纳入排除标准纳入326个周期(针刺组155、对照组171),对两组之间的基线水平及冷冻解冻胚胎移植过程中各参数进行统计学分析,并通过二元逻辑回归方式分析针刺治疗对临床妊娠结局的影响.结果:针刺组与对照组相比获得更高的临床妊娠率[48.4%vs31.0%,校正后OR:1.141,95%CI:0.356-1.349,P=0.001].两组在种植率[35.6%vs22.9%,校正后OR:0.938,95%CI:(0.808-1.077),P=0.176]、活产率[31.0%vs24.6%,校正后OR:0.935,95%CI:0.810-1.219,P=0.067]和早期流产率[12.9%vs5.8%,校正后OR:0.841,95%CI:0.775-2.125,P=0.122]上差异无统计学意义.结论:针刺疗法可以提高体外受精-胚胎移植患者的冷冻解冻胚胎移植周期的临床妊娠率.
Acupuncture Improves the Clinical Pregnancy Rate of Patients with Frozen-thawed Embryo Transfer: a Retrospective Cohort Study
Objective: To explore the effect of acupuncture therapy on pregnancy outcomes of frozen embryo transfer during in vitro fertilization-embryo transfer. Research content: Retrospective analysis of the data of patients who under-went frozen-thawed embryo transfer in the reproductive center from January 2019 to December 2021, and 326 cycles (155 in the acupuncture group and 171 in the control group) were included according to the inclusion and exclusion criteria. Statistical analysis was performed on the baseline levels between patients and various parameters during frozen-thaw em-bryo transfer, and the impact of acupuncture treatment on clinical pregnancy outcomes was analyzed through binary logis-tic regression. Results: Compared with the control group, the acupuncture group achieved a higher clinical pregnancy rate [48.4% vs 31.0%, adjusted OR: 1.141, 95%CI: 0.356-1.349, P=0.001]. The two groups were better at implantation rate [35.6% vs 22.9%, adjusted OR: 0.938, 95% CI: (0.808-1.077), P=0.176], live birth rate [31.0% vs 24.6%, adjusted OR:0.935 , 95%CI: 0.810-1.219, P=0.067] and early miscarriage rate [12.9% vs 5.8%, adjusted OR: 0.841, 95%CI: 0.775-2.125, P=0.122]. There is no statistically significant difference. Conclusion: Acupuncture therapy can improve the clinical pregnancy rate of frozen-thawed embryo transfer cycles in in vitro fertilization-embryo transfer patients.

Acupuncture treatmentFreeze-thaw transplantationClinical pregnancy rate

孙俊建、温树云

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北京市第一中西医结合医院 北京 100026

北京市朝阳区东坝第二社区卫生服务中心 北京 100018

针刺治疗 冷冻解冻移植 临床妊娠率

北京市朝阳区科技计划

CYSF2043

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(4)
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