首页|基于肺-肠轴探讨中西医干预哮喘的研究进展

基于肺-肠轴探讨中西医干预哮喘的研究进展

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支气管哮喘是临床常见的一种以气道慢性炎症为特征的呼吸系统疾病,其发病机制尚不明确.近年来,微生物学和分子生物学的快速发展让"肺-肠轴"这一概念成为新的热点.肺-肠轴是指存在于呼吸系统与肠道微生物之间的相互作用和调节机制,这个观点与中医"肺与大肠相表里"理论所见略同.随着哮喘疾病的不断增多,肺-肠轴成为一个备受关注的课题,深入研究肺-肠轴或有助于寻找治疗哮喘的新靶点.临床经验表明,中西医结合治疗哮喘可显著改善肺功能指标和临床评估标准,并能够降低哮喘的复发率和控制药物的使用量.其中,西医以抗生素药物为治疗哮喘的主要手段,具有见效快的优势,但也容易引起不良反应.中药治疗具有减轻哮喘症状、不良发应少和改善生活质量等显著优势,其中的针灸和推拿等中医技术均可增强防御力和调节免疫功能.中西医结合干预哮喘有着明显的临床疗效和广阔的应用前景.故该研究通过肺-肠轴理论阐述中西医干预哮喘的研究进展,以细致深入的进行机制探究,旨在为临床通过肺-肠轴理论采取合理的中西医干预哮喘措施提供依据.
Discussion on the Research Progress of Chinese and Western Medicine Intervention in Asthma based on the Theory of Lung-gut Axis
Bronchial asthma is a common clinical respiratory disease characterized by chronic inflammation of the airways, and its pathogenesis remains unclear. In recent years, the rapid development of microbiology and molecular biology has made the concept of "lung-gut axis" a new hot topic. The lung-gut axis refers to the interaction and regu-latory mechanism that exists between the respiratory system and intestinal microorganisms. This view is similar to the theory of "the lungs and the large intestine are externally and internally" in traditional Chinese medicine. With the in-creasing number of asthma diseases, the lung-gut axis has become a topic of great concern. In-depth study of the lung-gut axis may help to find new targets for the treatment of asthma. Clinical experience shows that the combination of traditional Chinese and Western medicine in the treatment of asthma can significantly improve lung function indicators and clinical evaluation standards, and can reduce the recurrence rate of asthma and control the use of drugs. Among them, Western medicine uses antibiotics as the main method to treat asthma, which has the advantage of quick results, but it is also easy to cause adverse reactions. Traditional Chinese medicine treatment has significant advantages in re-ducing asthma symptoms, reducing adverse reactions, and improving quality of life. Among them, traditional Chinese medicine techniques such as acupuncture and massage can enhance defense and regulate immune function. Integrating traditional Chinese and Western medicine to intervene in asthma has obvious clinical efficacy and broad application prospects. Therefore, this study explains the research progress of traditional Chinese and Western medicine in asthma intervention through the lung-gut axis theory, and conducts detailed and in-depth mechanism exploration, aiming to provide a basis for clinically adopting reasonable traditional Chinese and Western medicine intervention measures for asthma through the lung-gut axis theory.

Lung-gut axisTraditional Chinese and Western medicine interventionBronchial asthma

庞欣、梁文华

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山东中医药大学 山东济南 250000

山东省青岛市中医医院 山东青岛 266000

肺肠轴 中西医干预 支气管哮喘

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(4)
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