Systematic Evaluation of Acupuncture Combined with Medicine in Treatment of Ulcerative Colitis
Objective:To asess the efficacy and safety of acupuncture combined with western medicine in treatment of ulcerative colitis(UC).Method:The randomized controlled trials of combined acupuncture and medication for UC were collected,and the included literatures were stratified according to different treatment strategies.The quality of included literatures was evaluated by the Cochrane collaboration's bias risk assessment tool,and included literatures were systematically evaluated.Results:A total of 23 articles met the inclusion criteria.The results of meta-analysis suggested that the effective rate was the outcome index of the combined acupuncture and drug therapy group compared with the conventional treatment group,and the combined OR was 4.81,95％CI[3.63,6.37].Syndrome indicators of traditional Chinese medicine,abdominal pain,diarrhea,pus and blood stools were outcome indicators,and their combined SMD was-0.92,-1.93,-1.68,95％CI was[-1.34,-0.50],[-2.94,-0.92],[-2.67,-0.70],respectively.Geboes scale score was the outcome index,and its SMD was-3.09,95％CI[-8.06,1.89].Patient satisfaction was the outcome index,RR was 1.26,95％CI was[1.09,1.45].The outcome index was hospitalization expense,SMD was-9.93,95％CI[-11.83,-8.56].The outcome index was length of stay,and MD was-20.39,95％CI[-32.70,-8.07].All the indicators of the two groups were compared,except that there was no significant difference in the Geboes scale score,and all the other outcome indicators were statistically significant.Conclusion:The evaluation results of this system showed that the combination of acupuncture and drug therapy for UC could significantly improve the clinical ef-ficacy,significantly improve the clinical manifestations of abdominal pain,diarrhea,pus and blood stools,improve the satisfaction of patients,reduce the length of stay in hospital,reduce the cost of hospitalization,and no serious adverse reactions were observed,Therefore,acupuncture and medicine combination therapy is the best combination to treat this disease.Due to the relatively low quality of the included studies,more and higher quality studies are needed for further analysis.
combination of acupuncture with medicineulcerative colitisrandomized controlled trialssystematic reviewmeta analysis
国家科技期刊平台
NSTL
万方数据
