Effect of Modification Dasaihu Decoction on Dampness-heat Syndrome and Liver Function in Patients with Choledocholithiasis
Objective:To explore the effect of modified Dachaihu decoction on heat syndrome and liver function in patients with damp-heat syndrome of common bile duct stones.Methods:118 patients with common bile duct stones and damp-heat syndrome who met the standards in our hospital from June 2021 to June 2023 were selected as the re-search subjects.All patients receive basic treatment:necessary anti-infection,analgesic,liver-protective treatment and surgical treatment according to the patient's condition.In addition,modified and subtracted Dachaihu decoction treatment was implemented.Observe the total effective rate,TCM symptom scores,changes in liver function indica-tors,changes in inflammatory factor levels,and complications before and after treatment with the modified Da Chaihu Decoction.Results:The total effective rate after treatment with modified Dachaihu decoction(96.61％)was higher than before treatment(89.83％).After x2 test,the difference was statistically significant(x2=4.29 1,P=0.038).The TCM symptom scores after treatment with modified Dachaihu decoction were lower than before treatment.The t test showed that the difference was statistically significant(P＜0.05).The liver function indicators ALT,AST,TBIL,and GGT after treatment with modified Dachaihu decoction were all lower than before treatment.The t test showed that the differences were statistically significant(P＜0.05).IL-6 and TNF-α after treatment with Da Chaihu Decoction were lower than be-fore treatment,and IL-10 was higher than before treatment,with significant differences(P＜0.05).Among the 118 pa-tients,there were 2 cases of acute pancreatitis and 3 cases of acute cholangitis.,the overall complication rate was 4.24％.Conclusion:Modified Dachaihu Decoction can significantly improve liver function and reduce inflammatory response in patients with damp-heat syndrome due to common bile duct stones,with few complications and high safety.It can im-prove the treatment effect and promote the recovery of patients.
Modified Dachaihu DecoctionCommon bile duct stonesDamp-heat syndromeLiver function
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