首页|益肾活血逐瘀方联合甲钴胺片治疗腰椎间盘突出症微创术后残余神经痛临床观察

益肾活血逐瘀方联合甲钴胺片治疗腰椎间盘突出症微创术后残余神经痛临床观察

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目的:分析腰椎间盘突出症(Lumbar disc herniation,LDH)微创术后残余神经痛患者应用益肾活血逐瘀方联合甲钴胺片的治疗效果及其对腰椎功能、炎症因子水平的影响.方法:2020年3月-2023年3月,选取河南鹤壁浚县人民医院126例LDH微创术后残余神经痛患者作为研究对象,以随机数字表法分为两组.基础组63例给予甲钴胺片治疗,实验组63例增加益肾活血逐瘀方治疗.4周后,比较2组患者临床疗效、腰椎功能、炎症因子水平、不良反应.结果:实验组总有效率高于基础组(95.24%>84.13%)(P<0.05);实验组腰椎前屈最大肌力、腰椎后伸最大肌力、腰椎前屈最大活动度、腰椎后伸最大活动度均高于基础组(P<0.05);实验组白细胞介素-1、肿瘤坏死因子-α、白细胞介素-6水平均低于基础组(P<0.05);2组均未出现明显不良反应.结论:益肾活血逐瘀方联合甲钴胺片治疗能够有效改善LDH术后残余神经痛患者腰椎功能,减轻炎症反应,提高治疗效果,且安全性高.
The Effect of Yishen Huoxue Zhuyu Recipe Combined with Methylcobalamin Tablets in the Treatment of Residual Neuralgia after Minimally Invasive Surgery for Lumbar Disc Herniation and its Effect on Lumbar Spine Function and Inflammatory Factor Levels
Objective:To analyze the therapeutic effect of Yishen Huoxue Zhuyu Recipe combined with methylco-balamin tablets in patients with residual neuralgia after minimally invasive lumbar disc herniation(LDH)surgery and its impact on lumbar spine function and inflammatory factor levels.Methods:From March 2020 to March 2023,126 patients with residual neuralgia after minimally invasive LDH surgery at Hebi Junxian People's Hospital in Henan were selected as research subjects and divided into two groups using the random number table method.Sixty-three cases in the basic group were treated with methylcobalamin tablets,and 63 cases in the experimental group were addi-tionally treated with Yishen Huoxue Zhuyu Recipe.After 4 weeks,the clinical efficacy,lumbar function,inflammatory factor levels,and adverse reactions of the two groups of patients were compared.Results:The total effective rate of the experimental group was higher than that of the basic group(95.24%>84.13%)(P<0.05);the maximum muscle strength of lumbar forward flexion,the maximum muscle strength of lumbar posterior extension,the maximum range of lumbar forward flexion and lumbar posterior extension of the experimental group The maximum activity range was higher than that of the basic group(P<0.05);the levels of interleukin-1,tumor necrosis factor-α,and interleukin-6 in the experi-mental group were all lower than those of the basic group(P<0.05);there were no symptoms in either group Obvious adverse reactions.Conclusion:The treatment of Yishen Huoxue Zhuyu Recipe combined with methylcobalamin tablets can effectively improve the lumbar function of patients with residual neuralgia after LDH surgery,reduce the inflamma-tory reaction,improve the treatment effect,and is highly safe.

Yishen Huoxue Zhuyu RecipeLumbar disc herniationResidual neuralgiaLumbar functionInflam-matory factors

周志斌、张秀妮、申云楼

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河南鹤壁浚县人民医院 河南鹤壁 456250

河南省骨科医院 河南郑州 450000

益肾活血逐瘀方 腰椎间盘突出症 残余神经痛 腰椎功能 炎症因子

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(6)