Study on the Mechanism of TLR4/MyD88/NF-KB Signaling Pathway Mediated by Traditional Chinese Medicine in Primary Sj?gren's Syndrome
Primary Sjögren's syndrome(pSS)is a common disease in rheumatology and immunology,which trou-bles a large number of patients.It not only brings physical and psychological burdens to patients,but also creates huge economic pressures due to long-term clinical medication.The TLR4/MyD88/NF-κ B signaling pathway is involved in the occurrence,development and treatment of pSS.Traditional Chinese medicine has its advantages in the treatment of pSS.Both single-flavor medicine and compound medicine have significant clinical effects.Exploring the mechanism of traditional Chinese medicine in treating pSS based on the TLR4/MyD88/NF-κ B signaling pathway is of great signifi-cance to traditional Chinese medicine and clinical diagnosis and treatment of pSS.
Primary Sjögren's syndromeTLR4/MyD88/NF-κ B signaling pathwayTraditional Chinese medicine
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