Dry mouth is a common clinical symptom,which belongs to the category of"dryness syndrome"and"dryness arthralgia"in traditional Chinese medicine.At present,Western medicine still lacks understanding of the pathogenesis of this disease,and there is no specific medicine for treatment.Professor HAN Mingxiang is a national famous traditional Chinese medicine doctor and the leader of the key discipline of traditional Chinese medicine inter-nal medicine in Anhui Province.He has rich clinical experience and clever use of medicine.He has unique insights and definite efficacy in the treatment of dry mouth.Professor HAN Mingxiang proposed that the location of dry mouth is spleen,stomach,lung and kidney.It is proposed that the pathogenesis of dry mouth is mostly due to damp-heat ob-struction and kidney yin deficiency.Excessive syndrome is mostly caused by the lack of body fluid.Such patients usu-ally like to eat fatty and greasy food,which damages the spleen and stomach;deficiency syndrome is mostly seen in a variety of chronic diseases that have been prolonged for a long time,and body fluid is damaged.He has a lot of experi-ence in the clinical diagnosis and treatment of dry mouth,and believes that it should be differentiated and treated from the two aspects of clearing heat and dampness and nourishing kidney yin.He has repeatedly achieved good results in diagnosis and treatment.Now two cases are selected to provide reference for clinical practice.