Effect of Exercise Therapy Combined with Jiuwei Gujin Capsule on Pulmonary Function of COPD Patents with Lung-kidney Concurrent Deficiency in Stable Stage
Objective:To study the effect of exercise therapy combined with Jiuwei Gujin capsule on lung function in patients with lung and kidney deficiency in stable COPD. Methods:A total of 114 patients with lung and kidney de-ficiency in stable COPD who met the criteria in Shanxi Provincial Hospital of Traditional Chinese Medicine were ran-domly divided into group A:exercise training+Jiuwei Gujin capsule group (n=27),group B:Jiuwei Gujin capsule group (n=29),group C:exercise training group (n=28),and group D:basic treatment group (n=30). Groups A,B,and C were treated with exercise training combined with Jiuwei Gujin capsule,Jiuwei Gujin capsule,and exercise training,respec-tively,on the basis of group D. The treatment cycle was 1 month,and the lung function indexes (FEV1/FVC%,FEV1%) and arterial blood gas indexes (PaO2,PaCO2) were observed in each group. Results:Compared with before treatment,the lung function (FEV1/FVC%,FEV1%),PaO2 of the four groups and PaCO2 of group A were improved,and the dif-ference was statistically significant (P<0.01). There was no significant difference in PaCO2 before and after treatment in groups B,C and D (P>0.05). Compared with group D,the lung function (FEV1/FVC%,FEV1%) and PaO2 of group A were significantly improved after treatment,and the difference was statistically significant (P<0.05). After treatment,there was no significant difference in lung function (FEV1/FVC%,FEV1%) between group B and group C (P>0.05),but there was a significant difference in PaO2,and group C was stronger than group B. Jiuwei Gujin capsule and exer-cise training improved lung function (FEV1/FVC%,FEV1%),and the interaction between the two was not significant (P>0.05). The combined use was not as good as exercise training alone. For improving PaO2,the interaction between the two was significant (P<0.05),and the combined use had the best effect. Conclusion:Exercise therapy combined with Jiuwei Gujin capsule can effectively improve the lung function of patients with lung and kidney deficiency in the stable stage of COPD.
Exercise therapyJiuwei Gujin capsuleChronic obstructive pulmonary diseaseLung and kidney deficiencyLung functionBlood gas analysis