首页|运动疗法联合九味固金胶囊对慢性阻塞性肺疾病稳定期肺肾两虚型患者肺功能的影响

运动疗法联合九味固金胶囊对慢性阻塞性肺疾病稳定期肺肾两虚型患者肺功能的影响

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目的:研究运动疗法联合九味固金胶囊对慢性阻塞性肺疾病(COPD)稳定期肺肾两虚型患者肺功能的影响.方法:将山西省中医院符合标准的114例COPD稳定期肺肾两虚型患者按随机数字表法分为A组:运动训练+九味固金胶囊组(n=27)、B组:九味固金胶囊组(n=29)、C组:运动训练组(n=28)、D组:基础治疗组(n=30).A、B、C组在D组基础上分别加用运动训练联合九味固金胶囊、九味固金胶囊、运动训练,治疗周期为1月,观察各组肺功能指标(FEV1/FVC%、FEV1%)、动脉血气指标(PaO2、PaCO2).结果:与治疗前相比,4组肺功能(FEV1/FVC%、FEV1%)、PaO2、A组PaCO2均有改善,差异具有统计学意义(P<0.01),B组、C组、D组PaCO2治疗前后无明显差异(P>0.05).与D组相比,治疗后A组肺功能(FEV1/FVC%、FEV1%)、PaO2显著改善,差异具有统计学意义(P<0.05).治疗后B组与C组相比肺功能(FEV1/FVC%、FEV1%)无明显差异(P>0.05),而PaO2有显著差异,C组强于B组.九味固金胶囊和运动训练对于改善改善肺功能(FEV1/FVC%、FEV1%),二者交互作用不显著(P>0.05),合用不如单用运动训练,对于改善PaO2,二者交互作用显著(P<0.05),联合使用效果最好.结论:运动疗法联合九味固金胶囊可以较好改善COPD稳定期肺肾两虚型患者的肺功能.
Effect of Exercise Therapy Combined with Jiuwei Gujin Capsule on Pulmonary Function of COPD Patents with Lung-kidney Concurrent Deficiency in Stable Stage
Objective:To study the effect of exercise therapy combined with Jiuwei Gujin capsule on lung function in patients with lung and kidney deficiency in stable COPD. Methods:A total of 114 patients with lung and kidney de-ficiency in stable COPD who met the criteria in Shanxi Provincial Hospital of Traditional Chinese Medicine were ran-domly divided into group A:exercise training+Jiuwei Gujin capsule group (n=27),group B:Jiuwei Gujin capsule group (n=29),group C:exercise training group (n=28),and group D:basic treatment group (n=30). Groups A,B,and C were treated with exercise training combined with Jiuwei Gujin capsule,Jiuwei Gujin capsule,and exercise training,respec-tively,on the basis of group D. The treatment cycle was 1 month,and the lung function indexes (FEV1/FVC%,FEV1%) and arterial blood gas indexes (PaO2,PaCO2) were observed in each group. Results:Compared with before treatment,the lung function (FEV1/FVC%,FEV1%),PaO2 of the four groups and PaCO2 of group A were improved,and the dif-ference was statistically significant (P<0.01). There was no significant difference in PaCO2 before and after treatment in groups B,C and D (P>0.05). Compared with group D,the lung function (FEV1/FVC%,FEV1%) and PaO2 of group A were significantly improved after treatment,and the difference was statistically significant (P<0.05). After treatment,there was no significant difference in lung function (FEV1/FVC%,FEV1%) between group B and group C (P>0.05),but there was a significant difference in PaO2,and group C was stronger than group B. Jiuwei Gujin capsule and exer-cise training improved lung function (FEV1/FVC%,FEV1%),and the interaction between the two was not significant (P>0.05). The combined use was not as good as exercise training alone. For improving PaO2,the interaction between the two was significant (P<0.05),and the combined use had the best effect. Conclusion:Exercise therapy combined with Jiuwei Gujin capsule can effectively improve the lung function of patients with lung and kidney deficiency in the stable stage of COPD.

Exercise therapyJiuwei Gujin capsuleChronic obstructive pulmonary diseaseLung and kidney deficiencyLung functionBlood gas analysis

关炜、刘欢、康昱、成嘉欣

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山西省中医院 山西太原 030012

山西中医药大学 山西晋中 030619

运动疗法 九味固金胶囊 慢性阻塞性肺疾病 肺肾两虚 肺功能 血气分析

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(9)