Progress of PI3K/AKT/NF-κB Signaling Pathway in the Regulation of OSA
Obstructive Sleep Apnea (OSA) is a chronic disease characterized by frequent hypoxemia and hypercap-nia at night. In recent years,the incidence of OSA has been on the rise,which has attracted the attention of many schol-ars. At present,it is believed that the occurrence of OSA is closely related to pathological and physiological changes such as oxidative stress and inflammatory response. The PI3K/AKT/NF-κB signaling pathway plays an important role in regulating inflammatory response,oxidative stress,etc. Traditional Chinese medicine can effectively improve oxida-tive stress and inflammatory response by regulating the expression of the PI3K/AKT/NF-κB signaling pathway,and has achieved remarkable results. This article describes the specific mechanism of the PI3K/AKT/NF-κB signaling pathway in regulating OSA and the current research status of traditional Chinese medicine in regulating this pathway,providing new ideas for the treatment of OSA with traditional Chinese medicine.
Obstructive sleep apnea syndromePI3K/AKT/NF-κB pathwayTraditional Chinese medicineReview
万方数据
维普
