中医药临床杂志2024,Vol.36Issue(10) :1867-1872.DOI:10.16448/j.cjtcm.2024.1006

补气类中药对骨修复的调控作用及机制探讨

Complementing the Class Regulation Function and Mechanism of Qi-tonifying Chinese Medicine on bone Repair Function

庄晓杰 蔡尧天 张曦 高俊
中医药临床杂志2024,Vol.36Issue(10) :1867-1872.DOI:10.16448/j.cjtcm.2024.1006

补气类中药对骨修复的调控作用及机制探讨

Complementing the Class Regulation Function and Mechanism of Qi-tonifying Chinese Medicine on bone Repair Function

庄晓杰 1蔡尧天 1张曦 2高俊2
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作者信息

  • 1. 南京中医药大学附属常州市中医医院 江苏常州 213000
  • 2. 南京中医药大学附属常州市中医医院 江苏常州 213000;张曦江苏省名中医传承工作室 江苏常州 213000
  • 折叠

摘要

骨修复涉及多种细胞类型和细胞内外分子信号通路,许多补气类中药的有效成分在推动成骨细胞的生长与分化、保护软骨细胞等方面表现出显著的效果.这些补气类中药对骨修复的调控作用及作用机制具有一定的研究价值和实践意义.文章探讨了高频的9味补气类中药在骨修复方面的信号通路及作用机制,以期能够为未来的骨伤科相关疾病治疗提供新的思路和方法,同时也能够为开发新的中药药物提供理论支持和实践指导.

Abstract

Bone repair involves multiple cell types and intracellular and extracellular molecular signaling pathways.The active ingredients of many Qi-Tonifying Chinese medicines have shown significant effects in promoting the growth and differentiation of osteoblasts and protecting chondrocytes.The regulatory effects and mechanisms of these Qi-Ton-ifying Chinese medicines on bone repair have certain research value and practical significance.This paper discusses the signaling pathways and mechanisms of action of 9 high-frequency Qi-Tonifying Chinese medicines in bone repair,in order to provide new ideas and methods for the treatment of orthopedic-related diseases in the future,and also to provide theoretical support and practical guidance for the development of new Chinese medicines.

关键词

补气类中药/骨修复/骨关节炎/骨质疏松/信号通路/作用机制

Key words

Qi-Tonifying Chinese medicine/Bone repair/Osteoarthritis/Osteoporosis/Signaling pathway/Mecha-nism of action

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出版年

2024
中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
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