Analysis on Medication Law of Female Science Guideline in the Treatment of Ectopic leakage Based on Data Mining
Objective To analyze the prescription usage law of ectopic leakage in Female Science Guideline by using data mining method,and provide reference for clinical treatment of ectopic leakage.Methods All the oral prescriptions in the ectopic leakage section of Female Science Guideline were collected,and the usage frequency and meridian attribution of single herb were statistically analyzed by Exce12021.The drug association rules were analyzed by SPSS Modeler 18.0,and the high-frequency drugs with usage frequency ≥ 3 times were systematically clustered by SPSS Statistics 26.0.Re-sults 46 oral prescriptions were included,involving 99 herbs,with a total of 310 medication times.The herbs with higher usage frequency were angelica(29 times,9.40%),white peony(18 times,5.80%),and rehmannia(14 times,4.50%),with the main medicinal properties of warm(37 times,43.02%),cold(22 times,25.58%),the main flavors of sweet(40 times,27.78%),spicy(39 times,27.08%),and bitter(37 times,25.69%),and the main meridians of liver me-ridian(45 times,20.09%),kidney meridian(36 times,16.07%),and spleen meridian(35 times,15.62%).Based on the association rule analysis,30 core drug combinations with confidence ≥ 60.0%and support ≥ 15.0%were obtained,mainly white peony-angelica(18 times).A total of 10 core drug combinations were obtained by the high-frequency drug system cluster analysis.Conclusions In the treatment of ectopic bleeding in Female Science Guideline,the theory of"women take blood as the basic",and the treatment centering on liver,spleen and kidney,the four herbs of Siwu decoc-tion were used,and Qi,blood,yin and yang were supplemented.