目的:探究"针-药-模"结合治疗粉刺病肺胃热蕴证的临床效果.方法:收集2020年10月-2022年9月上海市嘉定区中医医院皮肤科门诊收治的粉刺病肺胃热蕴证患者150例,根据随机数字表法将其分为针-药-模治疗组(桑枇消痤颗粒+毫火针+石膏倒模)、针-药对照组(桑枇消痤颗粒+毫火针)、药-模对照组(桑枇消痤颗粒+石膏倒模),每组50例,均每周治疗1次,持续治疗4周.观察3组患者的临床疗效,比较3组治疗前后皮疹情况及生活质量[皮肤病生活质量指数量表(dermatology quality of life index,DLQI)],统计不良反应发生情况与复发率.结果:治疗4周后,针-药-模治疗组临床有效率高于针-药对照组、药-模对照组,差异有统计学意义;针-药对照组与药-模对照组比较,差异无统计学意义.3组患者皮疹情况评分、DLQI评分与治疗前比较均降低,且针-药-模治疗组低于针-药对照组及药-模对照组,差异有统计学意义;针-药对照组与药-模对照组比较,差异无统计学意义.治疗期间,3组患者不良反应发生情况比较,差异无统计学意义;结束治疗后2个月,针-药-模治疗组复发率低于针-药对照组、药-模对照组,差异有统计学意义;针-药对照组与药-模对照组比较,差异无统计学意义.结论:与"药-模"及"针-药"治疗相比,"针-药-模"相结合的综合治疗方法在粉刺病肺胃热蕴证的治疗中临床疗效更为显著,有效改善患者皮疹情况,提高生活质量,减少复发,安全性可靠.
Clinical Effect of the Combination of Acupuncture,Drug and Plaster Casting in the Treatment of Acne with Heat Accumulated in Lung and Stomach Syndrome
Objective:To explore the clinical effect of the combination of acupuncture,drug and plaster casting in the treatment of acne with heat accumulated in lung and stomach syndrome.Methods:A total of 150 patients with acne and heat accumulated in lung and stomach syndrome who were treated at Dermatology Department,Traditional Chinese Medicine Hospital of Jiading District,Shanghai from October 2020 to September 2022 were enrolled in this study.They were divided into the combined treatment group(Sangpi Xiaocuo Granules+filiform fire needle therapy+plaster cast-ing),the acupuncture-drug group(Sangpi Xiaocuo Granules+filiform fire needle therapy)and the drug-casting group(Sangpi Xiaocuo Granules+plaster casting),with 50 cases in each group.All patients were treated once a week,for 4 weeks.Clinical efficacy in the three groups was observed.The situation of skin rashes and quality of life[Dermatology Life Quality Index(DLQI)]of the three groups before and after treatment were comparatively analyzed.The incidence rates of adverse reactions and recurrence rate were calculated.Results:After 4 weeks of treatment,the total clini-cal effective rate of the combined treatment group was higher than those of the acupuncture-drug group and the drug-casting group(P＜0.05),there was no statistically significant difference between the acupuncture-drug group and the drug-casting group(P＞0.05).Skin rash scores and DLQI scores of the three groups were reduced.Meanwhile,above scores of the combined treatment group were lower than those of the acupuncture-drug group and the drug-casting group(P＜0.05),there was no statistically significant difference between the acupuncture-drug group and the drug-casting group(P＞0.05).The incidence rates of adverse reactions in the three groups were close(P＞0.05).The re-currence rate in the combined treatment group in 2 months after treatment was lower than those in the acupuncture-drug group and the drug-casting group(P＜0.05),there was no significant difference between the acupuncture-drug group and the drug-casting group(P＞0.05).Conclusion:Compared with drug-casting treatment and acupuncture-drug treatment,the combined treatment with acupuncture,drug and plaster casting can achieve more significant clini-cal effects in the treatment of acne with heat accumulated in lung and stomach syndrome.It can effectively relieve skin rashes,improve the quality of life and reduce recurrence.It is safe and reliable.
Acne with heat accumulated in lung and stomach syndromeCombination of acupuncture,drug and plaster castingFiliform fire needlePlaster castingSangpi Xiaocuo Granules
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